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Table 3 Log [EC10 (M)] and Log [EC50 (M)] values from the TH agonist TA assay (subdivided concentrations)

From: Determination of thyroidal endocrine-disrupting chemicals (EDCs) activities using a human cell-based transactivation assay

No. Test chemicals Log [EC10 (M)] Log [EC50 (M)]
#1 #2 #3 Ave SD %CV #1 #2 #3 Ave SD %CV
1 T3 − 9.31 − 9.25 − 9.39 − 9.32 0.07 0.75 − 8.11 − 7.86 − 8.01 − 7.99 0.13 1.58
2 T4 − 8.45 − 8.77 − 8.33 − 8.52 0.22 2.64 − 7.73 − 7.94 − 7.59 − 7.75 0.18 2.28
3 Tetrac − 7.55 − 7.61 − 7.51 − 7.56 0.05 0.71 − 6.53 − 6.68 − 6.57 − 6.59 0.08 1.15
4 GC−1 − 9.16 − 9.11 − 9.03 − 9.10 0.07 0.73 − 8.20 − 7.99 − 7.92 − 8.04 0.14 1.80
5 Triac − 9.36 − 9.24 − 9.33 − 9.31 0.07 0.70 − 8.48 − 8.52 − 8.62 − 8.54 0.07 0.83
  1. T3 3,3′,5-Triiodo-L−thyronine sodium salt
  2. T4 Levothyroxine sodium
  3. BPA Bisphenol A
  4. Tetrac 3,5,3′,5′-Tetraiodo Thyroacetic Acid
  5. GC-1 Sobetirome
  6. Triac 3,3′,5-Triiodothyroacetic acid