Determination of thyroidal endocrine-disrupting chemicals (EDCs) activities using a human cell-based transactivation assay

Environmental Sciences Europe

Table 3 Log [EC₁₀ (M)] and Log [EC₅₀ (M)] values from the TH agonist TA assay (subdivided concentrations)

No.	Test chemicals	Log [EC₁₀ (M)]						Log [EC₅₀ (M)]
No.	Test chemicals	#1	#2	#3	Ave	SD	%CV	#1	#2	#3	Ave	SD	%CV
1	T3	− 9.31	− 9.25	− 9.39	− 9.32	0.07	0.75	− 8.11	− 7.86	− 8.01	− 7.99	0.13	1.58
2	T4	− 8.45	− 8.77	− 8.33	− 8.52	0.22	2.64	− 7.73	− 7.94	− 7.59	− 7.75	0.18	2.28
3	Tetrac	− 7.55	− 7.61	− 7.51	− 7.56	0.05	0.71	− 6.53	− 6.68	− 6.57	− 6.59	0.08	1.15
4	GC⁻¹	− 9.16	− 9.11	− 9.03	− 9.10	0.07	0.73	− 8.20	− 7.99	− 7.92	− 8.04	0.14	1.80
5	Triac	− 9.36	− 9.24	− 9.33	− 9.31	0.07	0.70	− 8.48	− 8.52	− 8.62	− 8.54	0.07	0.83