Stirling A. Is the new European ruling on GM techniques ‘anti-science’? 2018. https://steps-centre.org/blog/european-court-of-justice-ecj-gene-editing-anti-science/. Accessed 22 Aug 2018
Judgement of the Court (Grand Chamber), 25 July 2018 in Case C-528/16. http://curia.europa.eu/juris/document/document.jsf;jsessionid=9ea7d0f130dcd5adc6577ba74dc9b5acf2530b87e485.e34KaxiLc3eQc40LaxqMbN4Pb3yRe0?text=&docid=204387&pageIndex=0&doclang=EN&mode=req&dir=&occ=first&part=1&cid=72898. Accessed 28 July 2018
Expert reaction to Court of Justice of the European Union ruling that GMO rules should cover plant genome editing techniques. http://www.sciencemediacentre.org/expert-reaction-to-court-of-justice-of-the-european-union-ruling-that-gmo-rules-should-cover-plant-genome-editing-techniques/. Accessed 1 Nov 2018
Friebe R, Warnecke T, Kühne A. Reaktionen auf den EuGH zur Gen-Schere CRISPR: “Ein richtig schlechtes Urteil”. 2018. https://www.tagesspiegel.de/wissen/reaktionen-auf-den-eugh-zur-gen-schere-crispr-ein-richtig-schlechtes-urteil/22851838.html. Accessed 30 Aug 2018
The Observer view on Europe’s ban on gene-editing crops. Observer editorial. https://www.theguardian.com/commentisfree/2018/jul/29/observer-view-on-europe-ban-on-gene-editing-crops. Accessed 1 Nov 2018
75 Forschungsinstitute fordern neues Gentechnikgesetz. http://www.spiegel.de/wissenschaft/natur/gentechnik-in-der-landwirtschaft-forschungsinstitute-plaedieren-fuer-neue-gesetze-a-1234773.html. Accessed 1 Dec 2018
Verband der Chemischen Industrie e. V. EuGH-Urteil zu Genome Editing “Rückwärtsgewandt und fortschrittsfeindlich”. 2018. https://www.vci.de/presse/pressemitteilungen/rueckwaertsgewandt-und-fortschrittsfeindlich-vci-zu-eugh-urteil-genome-editing.jsp. Accessed 4 Sept 2018
Salzberg S. EU court tries, but fails, to clarify rules on GMOs and CRISPR. https://www.forbes.com/sites/stevensalzberg/2018/07/30/eu-court-tries-but-fails-to-clarify-rules-on-gmos-and-crispr/#3e6592ad5022. Accessed 30 Nov 2018
Barrangou R (2018) CRISPR craziness: a response to the EU court ruling. CRISPR J. https://doi.org/10.1089/crispr.2018.29025.edi
Article
Google Scholar
Schadwinkel A. Dagegen aus den falschen Gründen. 2018. https://www.zeit.de/wissen/umwelt/2018-07/crispr-gentechnik-europaeischer-gerichtshof-urteil-kommentar. Accessed 30 July 2018
Beetham P. GMOs are not agriculture‘s future—Biotech IS. With new gene-editing techniques, the controversial technology will no longer be necessary. https://blogs.scientificamerican.com/observations/gmos-are-not-agricultures-future-biotech-is/. Accessed 29 Nov 2018
Hilbeck A, Binimelis R, Defarge N, Steinbrecher R, Székács A, Wickson F, Antoniou M, Bereano PL, Clark EA, Hansen M (2015) No scientific consensus on GMO safety. Environ Sci Eur 27:4
Article
Google Scholar
European Academies Science Advisory Council/EASAC. Planting the future: opportunities and challenges for using crop genetic improvement technologies for sustainable agriculture. 2013. EASAC policy report 21
European Environment Agency/EEA (2001) Late lessons from early warnings: the precautionary principle 1896–2000. Office for Official Publications of the European Communities, Luxembourg
Google Scholar
European Environment Agency/EEA (2013) Late lessons from early warnings: science, precaution, innovation. Publications Office of the European Union, Luxembourg
Google Scholar
McHenry LB (2018) The Monsanto papers: poisoning the scientific well. Inte J Risk Saf Med 29:193–205
Article
Google Scholar
Michaels D (2008) Doubt is their product. How industry‘s assault on science threatens your health. Oxford University Press, Oxford
Google Scholar
Borlaug NE (2000) Ending world hunger. The promise of biotechnology and the threat of antiscience zealotry. Plant Physiol 124:487–490
Article
CAS
Google Scholar
Tiedje JM, Colwell RK, Grossman YL, Hodson RE, Lenski RE, Mack RN, Regal PJ (1989) The planned introduction of genetically engineered organisms: ecological considerations and recommendations. Ecology 70:298–315
Article
Google Scholar
Is GM safe? http://www.bbc.co.uk/science/horizon/1999/gmfood_script.shtml. Accessed 30 Aug 2018
Vorschlag zur Einstufung neuer Methoden in der Pflanzenzucht. https://www.mpg.de/9943004/gen-editierte-pflanzen. Accessed 1 Sept 2018
World’s first gene-edited babies created in China, claims scientist. Unconfirmed scientific breakthrough sparks ethical and moral concerns. https://www.theguardian.com/science/2018/nov/26/worlds-first-gene-edited-babies-created-in-china-claims-scientist. Accessed 26 Nov 2018
European Network of Scientists for Social and Environmental Responsibility/ENSSER. ENSSER statement on new genetic engineering techniques, 2017. https://ensser.org/publications/ngmt-statement/. Accessed 1 Sept 2018
Fachstelle Gentechnik und Umwelt/FGU. Hintergrund: CRISPR/Cas (Risiken). 2018. https://fachstelle-gentechnik-umwelt.de/wp-content/uploads/CRISPR_Risiken.pdf. Accessed 1 Sept 2018
Steinbrecher R, Paul H (2013) New genetic engineering techniques: precaution, risk, and the need for develop prior societal technology assessment. Environ Sci Policy Sustain Dev 59(5):38–47
Article
Google Scholar
Bundesamt für Naturschutz/BfN. Hintergrundpapier zu Neuen Techniken. Neue Verfahren in der Gentechnik: Chancen und Risiken aus Sicht des Naturschutzes, 2017. https://www.bfn.de/fileadmin/BfN/agrogentechnik/Dokumente/17-07-13_Hintergrundpapier_Neue_Techniken_end_online_barrierefrei.pdf. Accessed 15 Aug 2018
McLeod C, Nerlich B (2017) Synthetic biology, metaphors and responsibility. Life Sci Soc Policy 13:13
Article
Google Scholar
O’Keefe M, Perrault S, Halpern J, Ikemoto L, Yarborough M (2015) Editing genes: a case study about how language matters in bioethics. Am J Bioeth 15:3–10
Article
Google Scholar
Sample I. Gene editing—and what it really means to rewrite the code of life. https://www.theguardian.com/science/2018/jan/15/gene-editing-and-what-it-really-means-to-rewrite-the-code-of-life. Accessed 31 Aug 2018
Haapaniemi E, Botla S, Persson J, Schmierer B, Taipale J (2018) CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response. Nat Med 24:927–930
Article
CAS
Google Scholar
Ihry RJ, Worringer KA, Salick MR, Frias E, Ho D, Theriault K, Kommineni S, Chen J, Sondey M, Ye C, Randhawa R, Kulkarni T, Yang Z, McAllister G, Russ C, Reece-Hoyes J, Forrester W, Hoffman GR, Dolmetsch R, Kaykas A (2018) p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells. Nat Med 24:939–946
Article
CAS
Google Scholar
Adikusuma F, Piltz S, Corbett MA, Turvey M, McColl SR, Helbig KJ, Thomas PQ (2018) Large deletions induced by Cas9 cleavage. Nature. https://doi.org/10.1038/s41586-018-0380-z
Article
Google Scholar
Kosicki M, Tomberg K, Bradley A (2018) Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements. Nat Biotechnol. https://doi.org/10.1038/nbt.4192
Article
Google Scholar
Yoshiyama KO, Kimura S, Maki H, Britt AB, Umeda M (2014) The role of SOG1, a plant-specific transcriptional regulator, in the DNA damage response. Plant Signal Behav. https://doi.org/10.4161/psb.28889
Article
Google Scholar
Ogita N, Okushima Y, Tokizawa M, Yamamoto YY, Tanaka M, Seki M, Umeda M (2018) Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis. Plant J 94:439–453
Article
CAS
Google Scholar
Vogel B. CRISPR-Pflanzen weltweit. Gen-ethischer Informationsdienst. 2018;25–27
Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH (1994) Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369:64–67
Article
CAS
Google Scholar
Horizon 2020: Biotechnology funding scheme. http://ec.europa.eu/programmes/horizon2020/en/news/h2020-fet-projects-biotechnologies. Accessed 15 Nov 2018
National Academies of Sciences, Engineering, and Medicine. 2016. Genetically engineered crops: experiences and prospects. Washington, DC. https://doi.org/10.17226/23395
Freese W, Schubert D (2004) Safety testing of genetically engineered food. Biotechnol Genet Eng Rev 21:299–324
Article
Google Scholar
Ruskin G. The FDA does not test whether GMOs are safe. https://usrtk.org/the-fda-does-not-test-whether-gmos-are-safe/ Accessed 15 Nov 2018
International Assessment of Agricultural Knowledge, Science and Technology for Development/IAASTD. Agriculture at a Crossroads. Global report. 2009 https://www.globalagriculture.org/fileadmin/files/weltagrarbericht/IAASTDBerichte/GlobalReport.pdf. Accessed 15 Aug 2018
International Service for the Acquisition of Agri-biotech Applications/ISAAA, PG Economics, Ltd. Brief 53: Global Status of Commercialized Biotech/GM Crops 2017. 2017. http://www.isaaa.org/resources/publications/briefs/53/. Accessed 3 Aug 2018
Quist DA, Heinemann JA, Myhr AI, Aslaksen I, Funtowicz S. Hungry for innovation: pathways from GM crops to agroecology. In: European Environment Agency/EEA 2013: Late lessons from early warnings: science, precaution, innovation. Luxembourg: Publications Office of the European Union; 2013, p. 458–485
Hakim D. Doubts about the promised bounty of genetically modified crops. https://www.nytimes.com/2016/10/30/business/gmo-promise-falls-short.html. Accessed 28 Aug 2018
Benbrook CM (2012) Impacts of genetically engineered crops on pesticide use in the U.S. The first sixteen years. Environ Sci Eur 24:24. https://doi.org/10.1186/2190-4715-24-24
Article
CAS
Google Scholar
Perry ED, Ciliberto F, Hennessy DA, Moschini GC (2016) Genetically engineered crops and pesticide use in U.S. maize and soybeans. Sci Adv. https://doi.org/10.1126/sciadv.1600850
Article
Google Scholar
Schütte G, Eckerstorfer M, Rastelli V, Reichenbecher W, Restrepo-Vassalli S, Ruohonen-Lehto M, Wuest Saucy AG, Mertens M (2017) Herbicide resistance and biodiversity: agronomic and environmental aspects of genetically modified herbicide-resistant plants. Environ Sci Eur 29:5. https://doi.org/10.1186/s12302-016-0100-y
Article
CAS
Google Scholar
Benbrook CM (2016) Trends in glyphosate herbicide use in the United States and globally. Environ Sci Eur 28:3
Article
Google Scholar
Gilbert N (2014) Cross-bred crops get fit faster. Genetic engineering lags behind conventional breeding in efforts to create drought-resistant maize. Nature 513:292
Article
CAS
Google Scholar
Gilbert N (2016) Frugal farming. Old-fashioned breeding techniques are bearing more fruit than genetic engineering in developing self-sufficient super plants. Nature. 533:308–310
Article
CAS
Google Scholar
Chen W, Provart NJ, Glazebrook J, Katagiri F, Chang HS, Eulgem T, Mauch F, Luan S, Zou G, Whitham SA, Budworth PR, Tao Y, Xie Z, Chen X, Lam S, Kreps JA, Harper JF, Si-Ammour A, Mauch-Mani B, Heinlein M, Kobayashi K, Hohn T, Dangl JL, Wang X, Zhu T (2002) Expression profile matrix of Arabidopsis transcription factor genes suggests their putative functions in response to environmental stresses. Plant Cell 14:559–574
Article
CAS
Google Scholar
Deinlein U, Stephan AB, Horie T, Luo W, Xu G, Schroeder JI (2014) Plant salt-tolerance mechanisms. Trends Plant Sci 19(6):371–379
Article
CAS
Google Scholar
Ramirez-Gonzalez RH, Borrill P, Lang D, Harrington SA, Brinton J, Venturini L, Uauy C (2018) The transcriptional landscape of polyploid wheat. Science. https://doi.org/10.1126/science.aar6089
Article
Google Scholar
Ober S. Bioökonomie. Forschungsfreiheit zwischen Wirtschaft und Politik. https://www.nabu.de/imperia/md/content/nabude/gentechnik/bio__konomie_2030_steffi_ober.pdf#_blank. Accessed 28 Aug 2018
Nearly half the experts from the European Food Safety Authority have financial conflicts of interest. https://corporateeurope.org/pressreleases/2017/06/nearly-half-experts-european-food-safety-authority-have-financial-conflicts. Accessed 22 Aug 2018
Then C. EFSA und Industrie vereinigt in ‘EFSI’. Neue Publikation zeigt enge Kooperation zwischen ExpertInnen der EFSA und der Gentechnik-Industrie. https://www.testbiotech.org/aktuelles/efsa-und-industrie-vereinigt-efsi. Accessed 22 Aug 2018
Vanloqueren G, Baret PV (2009) How agricultural research systems shape a technological regime that develops genetic engineering but locks out agroecological innovations. Res Policy 38:971–983
Article
Google Scholar
Bardgett RD, Gibson DJ (2017) Plant ecological solutions to global food security. J Ecol 105:859–864
Article
Google Scholar
Hilbeck A, Oehen B, editors. Feeding the people. Agroecology for nourishing the world and transforming the agri-food system. 2015. http://orgprints.org/30370/1/ifoameu_policy_ffe_feedingthepeople-2015.pdf. Accessed 22 Aug 2018
International Panel of Experts on Sustainable Food systems/IPES-Food. From uniformity to diversity: a paradigm shift from industrial agriculture to diversified agroecological systems. 2016. http://www.ipes-food.org/images/Reports/UniformityToDiversity_FullReport.pdf. Accessed 22 Aug 2018
Ledford H (2015) CRISPR, The Disruptor. Nature 522:20–24
Article
CAS
Google Scholar
Stone GD (2017) Dreading CRISPR: GMOs, honest brokers, and Mertonian transgressions. Geogr Rev 107:584–591
Article
Google Scholar
We take a science-based approach to GM regulation: UK to consider relaxing gene editing ban post Brexit. https://www.foodnavigator.com/Article/2018/09/14/UK-to-consider-relaxing-gene-editing-ban-post-Brexit Accessed 8 Sept 2018
Die Zeit. Newspaper edition: The grand hope (Die grosse Hoffnung). 27 June 2016. https://www.zeit.de/2016/27/emmanuelle-charpentier-crispr-gentechnik Accessed 11 Nov 2018