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Table 3 Multiple regression analysis of the association between a) U-8OHdG, and b) S-8OHdG concentrations, and some selected independent factors

From: Interplay of arsenic exposure and cigarette smoking on oxidative DNA damage in healthy males

Variables

Coefficient (β)

95% confidence interval

P-values

a) Log-Cr-adjusted-U8OHdG (µg/g Cr)

   

 As-ADI (mg/kg/day)

0.16

0.001, 0.004

0.01a

 Smoking duration (years)

0.27

− 0.002, 0.002

0.8

 Cigarettes smoked per day

0.14

− 0.001, 0.005

0.15

 U-tAs (µg/g Cr)

0.6

0.006, 0.009

< 0.001a

Physical activity

   

  Low

Ref

  

  Moderate

− 0.15

− 0.07, − 0.008

0.015a

  High

0.02

− 0.034, 0.05

0.7

b) S-8OHdG (ng/mL)

   

 As-ADI (mg/kg/day)

0.32

0.01, 0.037

0.001a

 Smoking duration (years)

0.3

− 0.014, 0.017

0.85

 Cigarettes smoked per day

0.3

0.000, 0.043

0.046a

 U-tAs (µg/g Cr)

0.08

− 0.006, 0.015

0.37

Physical activity

   

  Low

Ref

  

  Moderate

− 0.02

− 0.21, 0.25

0.84

  High

0.07

− 0.17, 0.44

0.4

  1. The models were adjusted for age and BMI, a Statistically significant