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Table 2 GLM results for the effect of arsenic exposure and cigarette smoking and their interaction on urinary and serum levels of 8-OHdG biomarker

From: Interplay of arsenic exposure and cigarette smoking on oxidative DNA damage in healthy males

GLM

df

Mean square

F

P-values

Log-Cr-adjusted-U8OHdG-arsenic exposure*cigarette smoking

    

 Arsenic exposure

1

0.23

19.37

< 0.001a

 Cigarette smoking

1

0.05

4.13

0.044a

 Arsenic exposure*cigarette smoking

1

0.03

2.9

0.09

 Age

1

0.17

14.15

< 0.001a

 BMI

1

0.01

0.85

0.36

 R-squared = 0.26 (adjusted R-squared = 0.24)

    

S-8OHdG-arsenic exposure*cigarette smoking

    

 Arsenic exposure

1

4.15

13.22

< 0.001a

 Cigarette smoking

1

1.25

3.97

0.048a

 Arsenic exposure*cigarette smoking

1

0.01

0.04

0.85

 Age

1

1.1

3.51

0.06

 BMI

1

0.006

0.02

0.89

 R-squared = 0.15 (adjusted R-squared = 0.11)

    
  1. Covariates: age, and BMI
  2. aStatistically significant