Table 1 EC50 and NOEC values of TBZ toxicity on C. elegans' reproduction applied as active substance (TBZ a.s.) in water and soil, and as commercial formulation (FOLICUR®) and nanoformulations (PCL-TBZ and NLC-TBZ) and the respective nanocarriers without TBZ in water; for the TBZ NF values are given in both units, freely dissolved TBZ concentrations and carrier nanoparticle concentrations;
Test item | TBZ (mg/L; mg/kg soil dw) | Particle concentration (particles/mL × 109) | ||
|---|---|---|---|---|
EC50 | NOEC | EC50 | NOEC | |
TBZ (a.s.) | ||||
Water | 29.7 ± 4.1 | <2.7 | – | |
Soil | 711 ± ± 12.3 | 501 | – | |
FOLICUR® | 16.0 ± 2.1a | 5.2 | – | |
PCL-TBZ | 11.5 ± 0.6a | 5.6 | 5.7 ± 0.06b | 4.4 |
NLC-TBZ | 6.40 ± 0.4a | 2.6 | 8.0 ± 0.29b | 4.4 |
PCL-carrier | – | 44.6 ± 4.0 | 8.6 | |
NLC-carrier | – | 11.7 ± 0.6 | 6.7 | |