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Environmental Sciences Europe

Table 1 Growth performance parameters of mice after TCA exposure for 21 days

From: Protective role of boron on hepatotoxicity and oxidative stress induced by trichloroacetic acid

Group

(mg/kg bw/day)

Body weight

(g)

Weight gain

(%)

Liver weight (g)

Liver weight as %

body weight

Control

28.6 ± 1.8

3.1 ± 1.1

1.41 ± 0.12

4.9% ± 0.00

25

28.2 ± 1.2

2.0 ± 1.5

1.50 ± 0.09

5.4% ± 0.00*

50

30.9 ± 0.7

2.3 ± 1.7

1.72 ± 0.13*

5.6% ± 0.00*

125

26.6 ± 0.5

2.7 ± 1.8

1.60 ± 0.06*

6.0% ± 0.00*

500

30.2 ± 1.3

2.2 ± 2.0

1.98 ± 0.13*

6.6% ± 0.00*

  1. TCA induces a statistically significant increase in the absolute liver weight and liver-to-body weight ratio at the doses of 50, 125, and 500 mg/kg/day groups. The data represent the mean ± SD of six mice for each of five groups. *p < 0.05 represents the statistical significance compared to the control group. Note: Bold values indicates significant differences compared to the control group
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