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Table 1 Available dataset for ratios calculated with the endpoints growth rate (ErC50) and the biomass-related endpoints—area under the curve (EbC50) or yield (EyC50) endpoints-ratios ErC50/EbC50and ErC50/EyC50-for various test species (algae and aquatic macrophytes), status of active substances (approved, not approved) and their class (herbicides or fungicides)

From: A critical examination of the protection level for primary producers in the first tier of the aquatic risk assessment for plant protection products

Ratio

Test category

n

Median

 ± 95% CI

Statistical test

p-value

Algae

 ErC50/EbC50

Test species

All species

177

2.33

2.08–2.53

 

Anabaena flos-aquaea

22

2.43

1.71–3.18

Kruskal–Wallis test

0.721

  

Desmodesmus subspicatusb

20

2.30

1.69–2.70

 
  

Raphidocelis subcapitatab

98

2.37

2.03–2.64

 
  

Navicula pelliculosac

27

2.17

1.77–2.67

 
  

Skeletonema costatumc

10

1.92

1.22–4.10

 
 

Status*

Approved

128

2.16

1.98–2.45

Wilcoxon rank sum test

0.066

Not approved

46

2.55

2.10–3.54

 

Class**

Herbicides

112

2.27

2.08–2.55

Wilcoxon rank sum test

0.946

Fungicides

63

2.37

1. 91–2.64

 ErC50/EyC50

Test species

All species

52

2.96

2.39–3.88

 

Anabaena flos-aquaea

6

2.69

1.89–7.62

Kruskal–Wallis test

0.643

  

Desmodesmus subspicatusb

3

2.59

 
  

Raphidocelis subcapitatab

37

3.65

2.39–4.66

 
  

Navicula pelliculosac

2

2.60

 
  

Skeletonema costatumc

4

2.03

 
 

Status*

Approved

31

2.61

1.89–4.19

Wilcoxon rank sum test

0.069

Not approved

19

3.38

2.67–6.25

 

Class

Herbicides

32

3.72

2.45–4.80

Wilcoxon rank sum test

0.151

Fungicides

20

2.59

1.75–3.38

Macrophytes

 ErC50/EbC50

Test species

Lemna spp.

40

1.60

1.18–1.92

 

Status*

Approved

26

1.56

1.00–1.80

Wilcoxon rank sum test

0.216

Not approved

13

2.16

0.64–3.58

 

Class

Herbicides

35

1.64

1.20–2.00

Wilcoxon rank sum test

0.513

Fungicides

5

1.16

 ErC50/EyC50

Test species

All species

28

2.08

1.79–2.45

 

Status

Approved

20

2.00

1.79–2.34

Wilcoxon rank sum test

0.304

Not approved

8

2.69

1.29–7.07

 

Class**

Herbicides

23

1.91

1.74–2.34

Wilcoxon

0.082

Fungicides

4

2.69

Rank sum test

 
  1. Information is given: “n" as number of entries, medians with ± 95% confidence intervals (CI), statistical tests used for comparing different groups and outcomes as p-values
  2. *Status "Pending" was excluded from further statistical analysis (for details, see Methods)
  3. **Substances labeled as both herbicide and fungicide (HU, FU) are excluded from further statistical analysis (for details, see Methods)
  4. aCyanobacteria, bGreen algae, cDiatom