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Table 1 List of statistically different proteins among the GMO and non-GM soybean varieties single-plot analyses which fall outside the reference varieties equivalence limits

From: Integration of omics analyses into GMO risk assessment in Europe: a case study from soybean field trials

Protein ID

GMO (± SD)

Non-GM (± SD)

p-adj

RVs tolerance interval

Proteins in the GMO falling outside RVs equivalence limits

 Plot 4

    

  I1KG57

1.2083 (± 0.04)

1.6010 (± 0.02)

0.025

[1.275, 1.874]

  I1LI58

0.5967 (± 0.02)

0.9899 (± 0.02)

0.011

[0.696, 1.293]

 Plot 5

    

  I1KXW8

0

0.6891 (± 0.04)

 < 0.001

[0.304, 1.669]

  A0A0R0HT35

0

0.9271 (± 0.14)

0.014

[0.400,1.598]

  A0A0R0EPX0

0

1.1651 (± 0.05)

 < 0.001

[0.346, 1.664]

  I1MFX5

0

1.0678 (± 0.08)

0.002

[0.181, 1.593]

Proteins in the non-GM plants falling outside RVs equivalence limits

  

 Plot 1

    

  A0A368UGC3

0.8394 (± 0.02)

0

0.004

[0.792, 1.325]

  I1K6K2

1.8341 (± 0.04)

0

0.009

[1.507, 2.522]

  Q42447

1.6765 (± 0.09)

0

0.022

[0.535, 2.907]

  I1L0T3

2.0508 (± 0.07)

0

0.014

[0.057, 5.402]

  A0A0R0HP07

1.1579 (± 0.03)

0

0.004

[0.696, 1.684]

 Plot 4

    

  I1JTZ7

1.4583 (± 0.06)

1.8714 (± 0.02)

0.031

[1.001, 1.598]

  I1JBW7

− 0.5662 (± 0.16)

2.0108 (± 0.24)

0.025

[− 2.662, 1.681]

  I1LF43

1.1062 (± 0.23)

0

0.025

[0.819, 2.081]

 Plot 6

    

 I1NAY9

0.6706 (± 0.04)

0

 < 0.001

[0.106, 1.382]

 Plot 7

    

  A0A0R0HJQ2

2.1241 (± 0.05)

− 0.3230 (± 0.03)

0.022

[0.999, 2.656]

  1. This table shows the protein UniProt ID; mean ± standard deviation expression values for the GMO and non-GM variety; false discovery rate adjusted p-value; and tolerance interval with 95% confidence, representing the equivalence limits of 99% of the values expressed in the population of reference varieties