|
Material
|
Chlorophyll measurement
|
Control
|
0.1 mg/L
|
1 mg/L
|
10 mg/L
|
1000 mg/L
|
|---|
|
Fibers
|
|
Cu
|
CV in vitro
|
12.7
|
65.6
|
39.2
|
–a
|
–a
|
|
CV in vivo
|
2.7
|
46.1
|
4.6
|
–a
|
–a
|
|
Ratio in vitro/in vivo
|
4.7
|
1.4
|
8.5
|
–a
|
–a
|
|
TiO2_fibers
|
CV in vitro
|
6.4
|
18.3
|
34.8
|
1.2
|
3.3
|
|
CV in vivo
|
1.2
|
2.3
|
1.5
|
0.1
|
0.3
|
|
Ratio in vitro/in vivo
|
81.2
|
43.7
|
67.7
|
760.1
|
305.2
|
|
SiC_thin
|
CV in vitro
|
13.8
|
14.0
|
33.5
|
55.8
|
32.3
|
|
CV in vivo
|
3.4
|
18.9
|
13.9
|
34.6
|
5.7
|
|
Ratio in vitro/in vivo
|
4.1
|
0.7
|
2.4
|
1.6
|
5.7
|
|
Platelets
|
|
Ag-ES-4
|
CV in vitro
|
18.1
|
17.8
|
20.0
|
16.1
|
0.0
|
|
CV in vivo
|
14.9
|
17.3
|
15.5
|
4.0
|
0.0
|
|
Ratio in vitro/in vivo
|
1.2
|
1.0
|
1.3
|
4.0
|
0.0
|
|
Spheres / compact particles
|
|
PMMA
|
CV in vitro
|
36.6
|
n.d.b
|
15.4
|
7.0
|
31.2
|
|
CV in vivo
|
5.7
|
n.d.b
|
6.3
|
5.1
|
8.4
|
| |
Ratio in vitro/in vivo
|
6.4
|
–a
|
2.4
|
1.4
|
3.7
|
|
PE_broad distribution
|
CV in vitro
|
8.5
|
n.d.b
|
n.d.b
|
17.7
|
11.5
|
|
CV in vivo
|
2.7
|
n.d.b
|
n.d.b
|
5.3
|
3.9
|
|
Ratio in vitro/in vivo
|
3.1
|
–a
|
–a
|
3.3
|
2.9
|
|
PA-6
|
CV in vitro
|
4.4
|
n.d.b
|
n.d.b
|
12.1
|
10.2
|
|
CV in vivo
|
4.7
|
n.d.b
|
n.d.b
|
2.5
|
9.1
|
|
Ratio in vitro/in vivo
|
0.9
|
–a
|
–a
|
4.8
|
1.1
|
|
IN718
|
CV in vitro
|
30.3
|
51.1
|
3.2
|
42.2
|
33.8
|
|
CV in vivo
|
23.1
|
45.3
|
9.0
|
40.3
|
38.4
|
|
Ratio in vitro/in vivo
|
1.3
|
1.1
|
0.4
|
1.0
|
0.9
|
|
Ti64
|
CV in vitro
|
15.8
|
17.5
|
21.9
|
25.5
|
11.0
|
|
CV in vivo
|
5.3
|
17.8
|
13.2
|
18.2
|
6.9
|
|
Ratio in vitro/in vivo
|
3.0
|
1.0
|
1.7
|
1.4
|
1.6
|
|
IN-Y2O3
|
CV in vitro
|
18.4
|
n.d.b
|
6.9
|
10.2
|
7.0
|
|
CV in vivo
|
13.4
|
n.d.b
|
6.8
|
9.4
|
2.4
|
|
Ratio in vitro/in vivo
|
1.4
|
n.d.b
|
1.0
|
1.1
|
2.9
|
|
Ti64-SiC
|
CV in vitro
|
10.3
|
36.8
|
22.8
|
9.7
|
4.5
|
|
CV in vivo
|
4.1
|
4.2
|
4.2
|
4.3
|
3.0
|
|
Ratio in vitro/in vivo
|
2.5
|
8.8
|
5.4
|
2.3
|
1.5
|
- a100% toxicity; no calculation possible. bn.d. = not determined
