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Environmental Sciences Europe
Fig. 3 | Environmental Sciences Europe

Fig. 3

From: Integrated high-throughput small RNA and transcriptome sequencing unveil the shape-dependent toxicity of nano-alumina in rat astrocytes

Fig. 3

Bubble plots reveal the KEGG pathway enrichment analysis of significantly differentially expressed miRNAs (A–C) and mRNAs (D–F) in rat ASTs exposed to two different shapes (flake or rod) of γ-Al2O3-NPs at 125 μg/mL for 72 h (n = 3). The vertical axis indicates the negative log(10) of Q value (FDR) of pathway enrichment analysis, and horizontal axis represents the number of genes annotated to the pathway, accounting for the proportion of the total number of genes. The size of the circle indicated the number of enriched miRNAs or genes. Group comparisons: Control vs Flake (A and D); Control vs Rod (B and E); Flake vs Rod (C and F)

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