Results from the European Union MAPEC_LIFE cohort study on air pollution and chromosomal damage in children: are public health policies sufficiently protective?

Environmental Sciences Europe

Table 3 Analysis of the associations between MN frequency and mutagenic activity of PM0.5, as detected by Ames test on 4 strains of Salmonella typhimurium (TA100, TA98, TA98NR, YG1021) with and without metabolic activation (S9)

Strain net revertants	IRR	95% CIs		P value
TA100	0.971	0.900	1.049	0.458
TA100 + S9	–	–	–	–
TA98	0.971	0.753	1.251	0.818
TA98 + S9	0.787	0.636	0.973	0.027
TA98NR	0.891	0.650	1.222	0.474
TA98NR + S9	0.917	0.625	1.347	0.660
YG1021	1.006	0.990	1.023	0.438
YG1021 + S9	0.998	0.988	1.009	0.718

All the associations were assessed including town of residence, temperature, child BMI and adherence to Mediterranean diet, exposure to second-hand smoke at home, having graduated mother and father in the model as potential confounders
The Incidence Rate Ratio (IRR), 95% Confidence Intervals (95% CIs) and p value are reported