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Table 3 Analysis of the associations between MN frequency and mutagenic activity of PM0.5, as detected by Ames test on 4 strains of Salmonella typhimurium (TA100, TA98, TA98NR, YG1021) with and without metabolic activation (S9)

From: Results from the European Union MAPEC_LIFE cohort study on air pollution and chromosomal damage in children: are public health policies sufficiently protective?

Strain net revertants IRR 95% CIs P value
TA100 0.971 0.900 1.049 0.458
TA100 + S9
TA98 0.971 0.753 1.251 0.818
TA98 + S9 0.787 0.636 0.973 0.027
TA98NR 0.891 0.650 1.222 0.474
TA98NR + S9 0.917 0.625 1.347 0.660
YG1021 1.006 0.990 1.023 0.438
YG1021 + S9 0.998 0.988 1.009 0.718
  1. All the associations were assessed including town of residence, temperature, child BMI and adherence to Mediterranean diet, exposure to second-hand smoke at home, having graduated mother and father in the model as potential confounders
  2. The Incidence Rate Ratio (IRR), 95% Confidence Intervals (95% CIs) and p value are reported