|
Pesticide
|
Type
|
ER activity
|
AhR activity
|
Nrf2 activity
|
|---|
|
r
|
p
|
r
|
p
|
r
|
p
|
|---|
|
Atrazine-desethyl
|
T (H)
|
0.26
|
0.0049
| | | | |
|
Azoxystrobin
|
F
|
0.31
|
0.0007
|
0.26
|
0.001
| | |
|
BAM
|
T (H)
|
0.35
|
0.0001
|
0.34
|
< 0.0001
| | |
|
Bitertanol
|
F
| | |
0.31
|
< 0.0001
|
0.33
|
0.0002
|
|
Boscalid
|
F
| | |
0.42
|
< 0.0001
| | |
|
Carbendazim
|
T (F)
|
0.28
|
0.0024
|
0.45
|
< 0.0001
| | |
|
Clomazone
|
H
| | |
0.43
|
< 0.0001
| | |
|
Chloridazon
|
H
| | |
0.25
|
0.0016
| | |
|
Diuron
|
H
| | |
0.40
|
< 0.0001
| | |
|
Diflufenican
|
H
| | |
0.48
|
< 0.0001
| | |
|
Flurtamone
|
H
| | |
0.24
|
0.0026
| | |
|
HCH-gamma (lindane)
|
I
| | |
0.43
|
< 0.0001
| | |
|
Isoproturon
|
H
| | |
0.46
|
< 0.0001
| | |
|
Mandipropamid
|
F
| | |
− 0.24
|
0.002
| | |
|
Methabenzthiazuron
|
H
|
0.50
|
< 0.0001
|
0.54
|
< 0.0001
| | |
|
Metalaxyl
|
F
| | |
− 0.30
|
0.0002
| | |
|
Metazachlor
|
H
| | |
0.44
|
< 0.0001
| | |
|
Methiocarb
|
I
|
0.40
|
< 0.0001
|
0.51
|
< 0.0001
| | |
|
Metrafenone
|
F
| | |
0.23
|
0.0039
| | |
|
Metribuzin
|
H
| | |
− 0.26
|
0.0008
| | |
|
Pirimicarb
|
I
|
0.32
|
0.0004
|
0.55
|
< 0.0001
| | |
|
Prothioconazole-desthio
|
T (F)
|
0.32
|
0.0005
|
0.47
|
< 0.0001
| | |
|
Propiconazole
|
F
|
0.35
|
0.0001
|
0.40
|
< 0.0001
| | |
|
Propyzamide
|
H
| | |
0.34
|
< 0.0001
| | |
|
Prosulfocarb
|
H
| | | | |
0.26
|
0.0036
|
|
Pyraclostrobin
|
F
|
0.28
|
0.0020
|
0.42
|
< 0.0001
| | |
|
Terbuthylazine
|
H
|
0.37
|
< 0.0001
|
0.52
|
< 0.0001
| | |
|
Terbuthylazine-desethyl
|
T (H)
|
0.43
|
< 0.0001
|
0.44
|
< 0.0001
| | |
|
Thiamethoxam
|
I
| | |
0.37
|
< 0.0001
| | |
- p values < 0.005 were considered as statistically significant
- H herbicide, F fungicide, I insecticide, T transformation product (of an H, F, or I)
