Table 2 Regression equation, linear range, and lower limit of quantitation concentrations (LLOQ) for the probe substrates used in incubations
From: Liver toxicity assessments in rats following sub-chronic oral exposure to copper nanoparticles
Analytes | Regression equation | Correlation coefficient (R2) | Linear range (ng/mL) | LLOQ (ng/mL) |
|---|---|---|---|---|
Phenacetin | y = 166.90x + 1.3728 | 0.9995 | 200–1400 | 50 |
Tolbutamide | y = 176.97x + 0.6415 | 0.9996 | 200–1400 | 50 |
Dextromethorphan | y = 128.91x + 1.3531 | 0.9999 | 200–1400 | 50 |
Chlorzoxazone | y = 110.85x + 4.8935 | 0.9999 | 200–1400 | 50 |
Testosterone | y = 212.16x + 49.721 | 0.9994 | 800–11,200 | 100 |