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Table 2 Regression equation, linear range, and lower limit of quantitation concentrations (LLOQ) for the probe substrates used in incubations

From: Liver toxicity assessments in rats following sub-chronic oral exposure to copper nanoparticles

Analytes Regression equation Correlation coefficient (R2) Linear range (ng/mL) LLOQ (ng/mL)
Phenacetin y = 166.90x + 1.3728 0.9995 200–1400 50
Tolbutamide y = 176.97x + 0.6415 0.9996 200–1400 50
Dextromethorphan y = 128.91x + 1.3531 0.9999 200–1400 50
Chlorzoxazone y = 110.85x + 4.8935 0.9999 200–1400 50
Testosterone y = 212.16x + 49.721 0.9994 800–11,200 100