Table 1 TKTD parameters and study-specific scaled functional response in Experiments 1 and 2
Symbol | Unit | DEB definition | Value |
|---|---|---|---|
\(\dot{h}_0\) | d−1 | Background hazard rate | 0.001545 |
\(\dot{k}_e\) | d−1 | Elimination rate constant | 0.0001283 |
\(c_0\) | ng/L | Threshold concentration for effects on feeding | 2.282e−09 |
\(c_T\) | ng/L | Tolerance concentration | 2.159 |
\(c_{0\text{s}}\) | ng/L | Threshold concentration for effects on survival | 0.6908 |
b | d−1 | Killing rate | 0.01965 |
\(f_{\text{cW0}}\) | − | Scaled functional response for Experiment 1 | 0.48 |
\(f_{\text{A}}\) | − | Scaled functional response for cohort A Experiment 2 | 0.73 |
\(f_{\text{B}}\) | − | Scaled functional response for cohort B Experiment 2 | 0.53 |
\(f_{\text{C}}\) | − | Scaled functional response for cohort C Experiment 2 | 0.73 |