Results of extended plant tests using more realistic exposure scenarios for improving environmental risk assessment of veterinary pharmaceuticals

Environmental Sciences Europe

Table 6 Measured concentrations of the test substances in highest application solution (florfenicol) and in spiked manure (tylosin tartrate), respectively, after anaerobic incubation for different periods of time

Substance	Day of incubation	Florfenicol^a recovery in highest application solution (%)	Tylosin tartrate^b recovery in spiked manure at representative test concentrations (%)
Standard test	–	n.d.	n.d.
Fresh spiked pig manure	0	85–95	6.0–38.2
Fresh spiked cattle manure	0	94–110	6.5–34.9
Half-max incubated pig manure	27	94–100	8.1–35.2
Half-max incubated cattle manure	45	103–104	16.7–27.1
Max incubated pig manure	53	94–100	11.4–31.9
Max incubated cattle manure	90	103–104	14.9–30.4

^aFlorfenicol was applied via an acetonic application solution
^bTylosin tartrate was applied via dry mixing into dung and analysed in pig manure at 0.228/1.365/4.0/7.1/17.8/45.5 mg/kg soil dry mass, in cattle manure at 0.228/1.365/4.0/7.1/17.8/45.5 mg/kg soil dry mass (fresh and maximum incubated manure) and at 0.228/1.365 (half-maximum incubated manure)