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Table 5 Fact-sheets for certain biomarkers and bioassays

From: The European technical report on aquatic effect-based monitoring tools under the water framework directive

  Fact-sheets of biomarkers and bioassays
Biomarker Metallothionein (MT)
ALA-D
Cytochrome P450 1A activity (EROD; CYP 1A activity)
DNA adducts
PAH metabolites
Liver histopathology (LH)
Macroscopic liver neoplasm (MLN)
Externally visible fish diseases
Reproductive success in eelpout
Vitellogenin
Intersex (in male fish)
Lysosomal stability
Imposex biomarkers
Micronucleus assay
Amphipod embryo alterations
Stress proteins (heat shock protein)
Acetylcholinesterase (AChE) assay
Comet Assay
Mussel histopathology (gametogenesis)
Stress on stress
Scope for Growth (SFG)
Benthic diatom malformation
Bioassay DR CALUX/DR Luc assay
PAH CALUX
ERα CALUX/ER-Luc (agonistic/antagonistic)
AR CALUX (agonistic/antagonistic)
YES
YAS
Ames fluctuation test
Micronucleus assay
Fish embryo acute toxicity (FET) test