Table 5 Identification criteria, extraction recoveries, LOD, LOQ, pKa and mass spectrometric detection parameters for the different SSRIs
From: Aerobic treatment of selective serotonin reuptake inhibitors in landfill leachate
Compound | pKa | [M + H] + (measured) | Fragment (measured) | Cone voltage | Collision energy | Retention time (min) | LOD (pg L −1 ) | LOQ (pg L −1 ) | Extraction recovery (%) |
|---|---|---|---|---|---|---|---|---|---|
Citalopram | 9.59 | 325.5 | 108.6 | 35 | 25 | 3.3 | 20 | 60 | 64/78a |
Desmethylcitalopram | 9.41 | 311.1 | 108.5 | 28 | 25 | 3.1 | 230 | 760 | - |
Didesmethylcitalopram | 10.14 | 297.1 | 108.5 | 29 | 20 | 2.9 | 200 | 780 | - |
Citalopram-D6 (IS) | - | 331.2 | 108.6 | 41 | 27 | 3.3 | - | - | - |
Paroxetine | 10.05 | 330.2 | 69.6 | 40 | 22 | 4.1 | 50 | 205 | 140/131a |
Paroxetine-D4 (IS) | - | 334.2 | 73.7 | 40 | 29 | 4.1 | - | - | - |
Fluvoxamine | 9.39 | 319.1 | 70.6 | 24 | 17 | 4.8 | 130 | 380 | 120/122a |
Fluoxetine | 10.05 | 310.1 | 43.8 | 22 | 15 | 6.0 | 150 | 490 | 110/84a |
Norfluoxetine | 9.05 | 296.1 | 133.7 | 15 | 5 | 5.5 | 160 | 540 | - |
Fluoxetine-D5 (IS) | - | 315.2 | 43.8 | 20 | 12 | 6.0 | - | - | - |
Sertraline | 9.47 | 306.1 | 158.6 | 18 | 25 | 6.4 | 160 | 520 | 100/133a |
Sertraline-D3 (IS) | - | 309.1 | 274.8 | 17 | 12 | 6.4 | - | - | - |