Ultrastructure of hepatocytes in male rats from groups presenting thegreatest degree of liver pathology. (1) Typical control rat hepatocyte(bar 2 μm except in 4). (2) Effects with Roundup at the lowestdose. Glycogen (G) is dispersed in the cytoplasm. L, lipid droplet; N, nucleus;R, rough endoplasmic reticulum. (3) Details of treatment effects with22% dietary GMO (bar 1 μm). a, cluster of residual bodies (asterisks); b,mitochondria show many enlarged cristae (arrows). (4) Hepatocytes ofanimal fed GM maize (GMO) at 22% of total diet. Large lakes of glycogen occurin the cytoplasm. M, mitochondria.