Table 2 Micronucleus test results of mouse bone marrow polychromatic erythrocytes
From: General toxicity and genotoxicity studies of a new scale inhibitor for seawater desalination
Groups | Dose mg/kg·BW | Female (n = 5) | Male (n = 5) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Total PCEs | PCEs with micronucleus | Micronucleus rate (‰) | p | Total PCEs | PCEs with micronucleus | Micronucleus rate (‰) | p | ||
Maleic acid polymer scale inhibitor | 1000 | 10,000 | 14 | 1.40 ± 0.84 | > 0.05 | 10,000 | 9 | 0.90 ± 0.84 | > 0.05 |
2000 | 10,000 | 29 | 2.90 ± 1.30 | > 0.05 | 10,000 | 13 | 1.30 ± 0.89 | > 0.05 | |
5000 | 10,000 | 28 | 2.80 ± 1.14 | > 0.05 | 10,000 | 15 | 1.50 ± 1.41 | > 0.05 | |
Negative control | — | 10,000 | 14 | 1.40 ± 1.30 | > 0.05 | 10,000 | 14 | 1.40 ± 1.10 | > 0.05 |
Positive control (Mitomycin C) | 1.0 | 10,000 | 185 | 18.5 ± 9.70 | < 0.01 | 10,000 | 175 | 17.5 ± 12.61 | < 0.01 |