Scoring scheme for Comparative Ranking of impact potential of chemical Alternatives (SCoRA)

Nendza, Monika; Hahn, Stefan; Klein, Michael; Klaschka, Ursula; Gabbert, Silke

doi:10.1186/s12302-023-00718-3

Environmental Sciences Europe

Table 1 Case study chemicals

From: Scoring scheme for Comparative Ranking of impact potential of chemical Alternatives (SCoRA)

Name	CAS	Chem. class	Bioaccumulation	Toxicity	PBTness	References
D4	556-67-2	siloxane	BCF_aquat	Toxic to aquatic and soil biota, CMR	vPvB	ECHA [20]
D5	541-02-6	siloxane	BCF_aquat	Toxic to aquatic and soil biota, indirect effects via food-chain	vPvB	ECHA [20], NIVA [21]
Anthracene	120-12-7	PAH	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota	vPvBT	NIVA [21], ECHA [22], EC [23]
Pyrene	129-00-0	PAH	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota	vPvBT	NIVA [21], EC [23], ECHA [24]
Benzo[a]pyrene	50-32-8	PAH	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota, indirect effects via food-chain, CMR	vPvBT	NIVA [21], EC [23], ECHA [25]
Lindane	58-89-9	pesticide	BAF_terrest	Toxic to aquatic and soil biota, indirect effects via food-chain, CMR	POP screening criteria fulfilled	NIVA [21], IPCS [26], WFD [27], UNEP [28]
DDT	50-29-3	pesticide	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota, indirect effects via food-chain, CMR	Restricted POP	NIVA [21], IPCS [29], Mackay et al. [30], EFSA [31], Kemakta [32]
HBCDD	25637-99-4, 3194-55-6, 134237-50-6, 134237-51-7, 134237-52-8	flame retardant	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota, CMR	PvBT	NIVA [21], ECHA [33]
DecaBDE	1163-19-5	flame retardant	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota, CMR	PBT/vPvB-forming substance	ECHA [34]
Dechlorane Plus	13560-89-9	flame retardant	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota, indirect effects via food-chain	vPvBT	Environment Canada [35], ECHA [36]
PFOA	335-67-1	PFAS	BAF_protein	Toxic to aquatic and soil biota, CMR	PBT	NIVA [21], OECD [37], ECHA [38],
PFOS	1763-23-1	PFAS	BAF_protein	Toxic to aquatic and soil biota, CMR	PBT	NIVA [21], UK Environment Agency [39], EFSA [40], LAWA [41]
Bisphenol A (BPA)	80-05-7	phenol	BAF_terrest	Toxic to aquatic and soil biota, CMR, ED	Not PBT	NIVA [21], ECHA [42, 43]
Dimethyl-propylphenol	80-46-6	phenol	BAF_terrest	Toxic to aquatic and soil biota, ED	Not PBT	UK Environment Agency [44], ECHA [45]
Nonylphenol	84852-15-3, 25154-52-3	phenol	BCF_aquat, BAF_terrest	Toxic to aquatic and soil biota, CMR, ED	Not PBT	NIVA [21], UK Environment Agency [44], ECHA [45, 46], EC [47]

BCF_aquat Bioconcentration potential in aquatic organisms and food chains due to log Kow > 4.5; BAF_terrest Bioaccumulation potential in air-breathing organisms due to log Kow > 2 and log Koa > 5; BAF_protein Bioaccumulation potential in organisms related to protein binding

Back to article page