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Table 2 Type of uses and the number of products or processes impacted by APE substitution

From: Experiences and consequences of phasing out substances of concern in a multinational healthcare company

Use type

Number of products or processes affected

Type of function of the alkylphenol ethoxylates

Use as an emulsifier in the siliconisation of glass containers used as primary packaging for medicinal products

2 medicinal products

Emulsifier in the silicone oil emulsion

Formulation, filling and use of in vitro diagnostic assays

23 products

Increasing the solubilisation of reagents, cell lysis, protein stabilisation and wetting agent

Use in the production of proteins and the conjugation of latex beads (use in the production of in vitro diagnostic assays)

19 processes*

Increasing solubilisation of reagents, cell lysis, protein extraction and protein stabilisation or dialysis

  1. *These processes impact a larger number of final products