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Fig. 6 | Environmental Sciences Europe

Fig. 6

From: Introducing oxygen transfer rate measurements as a novel method for time-resolved cytotoxicity assessment in shake flasks

Fig. 6

Dose–response curves of DMSO for CHO cell line two. A Dose–response curve for DMSO obtained by curve fitting using Eq. 1 with cytotoxicity values calculated with Eq. 2 by using measured OTR values of treated and control culture after 100 h. B Dose–response curve for DMSO obtained by curve fitting using Eq. 1 with cytotoxicity values calculated with Eq. 2 using ratio of determined slopes of treated and control culture. Each slope was calculated by linear fitting of the measured OTR values between 0 and 100 h (Additional file 1: Fig. S6). Data from experiment 6 (Additional file 1: Table S1). OTR data used for calculation are depicted in Fig. 5

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