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Table 2 Log [EC10 (M)] and Log [EC50 (M)] values from the TH agonist TA assay

From: Determination of thyroidal endocrine-disrupting chemicals (EDCs) activities using a human cell-based transactivation assay

No. Test chemicals Log [EC10 (M)] Log [EC50 (M)]
#1 #2 #3 Ave SD %CV #1 #2 #3 Ave SD %CV
1 T3 −9.89 −9.72 −9.69 −9.76 0.11 1.12 −8.73 −8.45 −8.45 −8.54 0.16 1.87
2 T4 −7.83 −7.77 −7.75 −7.78 0.04 0.55 −6.96 −6.75 −6.74 −6.82 0.12 1.77
3 Glycitein
4 BP-2
5 E2
6 BPA
7 Tetrac − 7.62 − 7.63 − 7.60 − 7.61 0.02 0.23 − 6.18 −6.29 − 6.24 − 6.24 0.05 0.86
8 GC-1 − 8.91 − 8.94 − 8.99 − 8.95 0.04 0.48 − 6.87 −6.94 − 7.46 − 7.09 0.32 4.52
9 Triac − 9.68 − 9.78 − 9.86 − 9.77 0.09 0.94 − 8.14 −8.27 − 8.46 − 8.29 0.16 1.91
10 Amiodarone hydrochloride
11 Hispidulin
12 Procymidone
13 Bithionol
14 Closantel
15 Rafoxanide
16 4,4'-Diiodobiphenyl
17 BDE No 28
  1. T3, 3,3′,5-Triiodo-l-thyronine sodium salt; T4, Levothyroxine sodium; BP−2, 2,2′,4,4′-Tetrahydroxybenzophenone; E2, 17β-Estradiol; BPA, Bisphenol A; Tetrac, 3,5,3′,5′-Tetraiodo Thyroacetic Acid; GC-1, Sobetirome; Triac, 3,3′,5-Triiodothyroacetic acid