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Table 5 Risk assessment and RQ comparison for the approach by EFSA [14] and AMiRA

From: An efficient and pragmatic approach for regulatory aquatic mixture risk assessment of pesticides

Species Risk according to EFSA [14] Risk according to AMiRA
Fish Acceptable, FOCUS step 3
FOCUS step 3:
RQa.s. = 0.8269 < 1
(based on single a.s. risk assessment)
Acceptable, FOCUS step 4 (5 m spray buffer)
FOCUS step 3:
RQmix = 1.0012 > 1
FOCUS step 4 (5 m):
RQmix = 0.6502 < 1
Daphnids Acceptable, FOCUS step 4 (10 m spray buffer + 10 m veg. strip)
FOCUS step 4 (10 m + 10 m):
RQa.s. = 0.5857 < 1
(based on single a.s. risk assessment)
Acceptable, FOCUS step 4 (10 m spray buffer + 10 m veg. strip)
FOCUS step 4 (10 m + 10 m):
RQmix = 0.5887 < 1
Algae Not acceptable, FOCUS step 4 (all buffer mitigations)
FOCUS step 4 (all mitig.):
RQmix = 5.9583 > 1a
(based on measured mixture toxicity)
Not acceptable, FOCUS step 4 (all buffer mitigations)
FOCUS step 4 (all mitig.):
RQmix = 4.5831 > 1a
Lemna Acceptable, FOCUS step 4 (20 m spray buffer + 20 m veg. strip)
FOCUS step 4 (10 m + 10 m):
RQmix = 1.0379 > 1
FOCUS step 4 (20 m + 20 m):
RQmix = 0.5438 < 1
(based on measured mixture toxicity)
Acceptable, FOCUS step 4 (10 m spray buffer + 10 m veg. strip)
FOCUS step 4 (10 m + 10 m):
RQmix = 0.5693 < 1
  1. aPlease note, that necessarily all RQmix > 2 (in case of two active substances in the mixture) consist of at least one single substance RQ > 1 leading to not acceptable risk even for a single substance risk assessment