Removal of oxidative stress and genotoxic activities during drinking water production by ozonation and granular activated carbon filtration

Environmental Sciences Europe

Table 3 Summary of bioequivalent concentrations (BEQs) based on the ECIR1.5 for Nrf2 and EC10 values for the AhR, and ER assays

Assay	RW		SF		BAC		UV		DW			GAC-B
Assay	Nov-19	May-20	Nov-19	May-20	Nov-19	May-20	Nov-19	May-20	Nov-19	May-20	Sep-20	Nov-19	May-20
Nrf2 activity tBHQEQ (μM)	0.42	0.05	0.86	0.04	0.69	0.05	0.65	0.06	(IA)	0.05	(IA)	(IA)	(IA)
AhR activity TCDDEQ (pM)	0.06	0.11	0.08	0.09	0.07	0.12	0.06	0.10	(IA)	0.08	0.16	(IA)	(IA)
ER activity E2EQ (pM)	0.07	0.07	0.07	0.09	0.03	0.06	0.05	0.07	(IA)	0.06	(IA)	(IA)	(IA)

“(IA)”—inactive. If the bioactivity at the highest REF value in the dilution series was below the cut-off limit for bioactivity, the EC and BEQ values were not calculated