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Fig. 4 | Environmental Sciences Europe

Fig. 4

From: Integrated high-throughput small RNA and transcriptome sequencing unveil the shape-dependent toxicity of nano-alumina in rat astrocytes

Fig. 4

MiRNA and gene interaction network analysis for the significantly differentially expressed genes in rat ASTs exposed to two different shapes (flake or rod) of γ-Al2O3-NPs at 125 μg/mL for 72 h (n = 3). A Control vs Flake; B Control vs Rod; C Flake vs Rod. The triangle and circle (nodes) represent the significantly differentially expressed miRNAs and genes, respectively. The thickness of the connecting line (edges) between miRNA and gene reflects the strength of their interactions. The node size represents the abundance of the expressions of miRNAs and genes. Red and green colors represent the positive and negative correlations, respectively

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