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Fig. 2 | Environmental Sciences Europe

Fig. 2

From: Integrated high-throughput small RNA and transcriptome sequencing unveil the shape-dependent toxicity of nano-alumina in rat astrocytes

Fig. 2

Volcano plots of miRNAs (A–C) and mRNAs (E–G) in rat ASTs exposed to two different shapes (flake or rod) of γ-Al2O3-NPs at 125 μg/mL for 72 h (n = 3). Each point represents a miRNA or mRNA, the expression level and negative logarithm of Q value (FDR) as the abscissa and ordinate, respectively. Pink and green dots represent the significantly up-regulated and down-regulated genes, respectively. Blue or gray dots represent miRNAs or mRNAs that were not differentially expressed. The total number of significantly differentially expressed genes is shown for miRNAs (D) and mRNAs (H). Group comparisons: Control vs Flake (A and E); Control vs Rod (B and F); Flake vs Rod (C and G)

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