Table 1 Comparison of 4-PL and 5-PL models fit to concentration–response data obtained from H4L7.5c2 rat hepatoma cells with the extra sum-of-squares (ESS) F test
Number of calibrators | Number of parameters | WSSR | DF | |
|---|---|---|---|---|
4-PL model (null hypothesis) | 9 | 4 | 20.867 | 5 |
5-PL model (alternative hypothesis) | 9 | 5 | 3.926 | 4 |
Difference | 16.941 | 1 | ||
Difference (%) | 431.51 | 25.00 | ||
Ratio (F) | 17.26 | |||
p value | 0.0142 | |||