TY - JOUR AU - Mueller, Carolin AU - Trapp, Stefan AU - Polesel, Fabio AU - Kuehr, Sebastian AU - Schlechtriem, Christian PY - 2020 DA - 2020/12/19 TI - Biomagnification of ionizable organic compounds in rainbow trout Oncorhynchus mykiss JO - Environmental Sciences Europe SP - 159 VL - 32 IS - 1 AB - The assessment of persistence, bioaccumulation and toxicity (PBT) is part of the regulation process of ionic organic compounds (IOCs) and a major challenge, as a commonly acknowledged approach for the estimation of the bioaccumulation potential of IOCs is still missing. The goal of the present study was, therefore, to experimentally determine the bioaccumulation of fully ionized compounds and to identify screening parameters that can indicate high bioaccumulation potential of IOCs. Three feeding studies with rainbow trout (Oncorhynchus mykiss) were carried out according to OECD TG 305. Separation of liver, gastrointestinal tract (GIT) and carcass allowed to further elucidate the tissue distribution of the individual test substances. The chemicals chosen had characteristics that made them suspect for high bioaccumulation, and included two cations (tetrabutylphosphonium bromide (TBP), trimethyloctadecyl ammonium chloride (TMOA)) and four anions (benzotriazole, tecloftalam, pentachlorophenol (PCP), MEE-phosphonate). Data on the dietary biomagnification of IOCs (strong acids) were also collected from published literature. SN - 2190-4715 UR - https://doi.org/10.1186/s12302-020-00443-1 DO - 10.1186/s12302-020-00443-1 ID - Mueller2020 ER -