Table 3 Biochemical biomarkers in juvenile brown trout exposed to citalopram and venlafaxine
Concentration (µg/L) | Citalopram | Venlafaxine | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 10 | 100 | 1000 | 0 | 1 | 10 | 100 | 1000 | |
AChE activity (mU/mg Protein) | 48.6 ± 13.8 | 54.6 ± 14.6 | 48.0 ± 9.6 | 48.6 ± 9.0 | 58.3 ± 16.0 | 70.6 ± 13.4 | 73.6 ± 12.5 | 73.1 ± 10.9 | 71.2 ± 11.6 | 69.6 ± 9.0 |
CbE activity (NPA substrate) (mU/mg Protein) | 66.6 ± 16.6 | 64.9 ± 17.7 | 63.4 ± 16.8 | 65.7 ± 17.7 | 61.6 ± 17.4 | 104.7 ± 20.2 | 111.4 ± 26.2 | 114.0 ± 19.0 | 113.1 ± 18.1 | 107.5 ± 19.6 |
CbE activity (NPV substrate) (mU/mg Protein) | 55.6 ± 23.3 | 50.1 ± 25.6 | 50.1 ± 24.7 | 51.2 ± 26.4 | 42.7 ± 24.7 | 94.7 ± 29.2 | 102.8 ± 32.4 | 106.1 ± 26.0 | 106.8 ± 24.6 | 97.3 ± 22.9 |
SOD activity (U/mL) | na | na | na | na | na | 88.4 ± 31.4 | 100.4 ± 38.9 | 91.6 ± 32.5 | 100.4 ± 31.1 | 107.9 ± 35.2 |
Hsp70 level (relative grey value) | 2.10 ± 0.35 | 2.21 ± 0.58 | 1.95 ± 0.43 | 2.02 ± 0.44 | 1.93 ± 0.41 | 2.06 ± 0.24 | 2.02 ± 0.24 | 2.06 ± 0.23 | 2.13 ± 0.31 | 1.90 ± 0.22 |