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Environmental Sciences Europe

Table 4 Time dependence (td) of single substance and mixture toxicity

From: Mixture toxicity analysis in zebrafish embryo: a time and concentration resolved study on mixture effect predictivity

Substance

td_lethal_early

td_lethal_late

Benzo[a]pyrene

*

*

Benzo[b]fluoranthene

*

*

Bisphenol A

0.658

0.680

Carbendazim

0.922

0.431

Chlorophene

0.402

0.473

Cyprodinil

1.102

0.422

Diazinon

1.124

0.866

Diclofenac

0.053

0.396

Diuron

1.045

*

Genistein

0.606

0.018

Naphthalene

1.126

0.554

Naproxen

0.604

0.241

Propiconazole

0.855

0.819

Triclosan

0.371

0.520

Triphenyl phosphate

0.755

0.982

Mean_single substances

0.740

0.534

mixA

–

0.223

mixB.1

0.978

–

mixB.2

–

0.713

mixC.1

0.848

–

mixC.2

–

0.525

mixD

–

–

mixE.1

0.330

0.556

mixE.2

0.636

0.362

mixF

–

0.712

mean_mixtures

0.698

0.561

  1. Shown is the time dependence (td) of toxicity for lethal effects obtained after starting exposures early (0 hpf) and late (24 hpf), respectively
  2. Td is the ratio LC50 (longest exposure duration) / LC50 (shortest exposure duration)
  3. * No CRC at tested concentrations, – no toxicity tested
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