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Table 2 Composition of investigated mixtures

From: Mixture toxicity analysis in zebrafish embryo: a time and concentration resolved study on mixture effect predictivity

 

Name of mixture

mixA

mixB.1

mixB.2

mixC.1

mixC.2

mixD

mixE.1

mixE.1

mixE.2

mixE.2

mixF

Experimental design

No. of compounds

3

5

5

5

5

10

12

12

12

12

13

Highest test conc. (µmol/L)

991.74

991.74

991.74

991.74

85.38

60.99

148.76

148.76

69.42

46.28

198.35

119.01

119.01

67.54

43.22

39.69

119.08

59.54

59.54

119.08

119.08

59.54

14.94

22.40

22.40

22.22

144.16

144.16

Exposure time (hpf)

24–96

0–48

24–72

0–48

24–72

24–96

0–96

24–96

0–96

24–96

24–96

df per experiment

1.6 1.6

1.5 1.3

1.4 1.4

1.3

1.25

1.5

1.5

1.8

1.4

1.25

1.25

1.15

1.12

1.5

1.3

1.3

1.5

1.5

1.3

1.2

1.3

1.2

1.25

1.12

1.15

Mixture ratio

Benzo[a]pyrene

     

0.0009

0.0005

0.0005

0.0006

0.0006

0.0004

Benzo[b]fluoranthene

     

0.0074

0.0008

0.0008

0.0006

0.0006

0.0034

Bisphenol A

 

0.3826

0.3342

  

0.2385

0.0058

0.0058

0.2768

0.2768

0.0369

Carbendazim

   

0.0277

0.0980

      

Chlorophene

     

0.0297

0.0750

0.0750

0.4251

0.4251

0.0045

Cyprodinil

 

0.0131

0.1061

0.0437

0.3130

0.0710

0.0083

0.0083

0.0124

0.0124

0.0110

Diazinon

 

0.0543

0.2021

  

0.2342

0.00005

0.00005

0.0013

0.0013

0.0363

Diclofenac

0.0210

  

0.3829

0.0755

 

0.2498

0.2498

0.1928

0.1928

0.0219

Diuron

0.0840

  

0.2071

0.1620

 

0.0050

0.0050

0.0138

0.0138

0.0927

Genistein

   

0.3386

0.3515

0.1089

0.0008

0.0008

0.0297

0.0297

0.0168

Naphthalene

 

0.5394

0.3542

        

Naproxen

0.8950

         

0.7281

Propiconazole

     

0.2648

0.4997

0.4997

0.0056

0.0056

0.0410

Triclosan

 

0.0106

0.0034

  

0.0040

0.0291

0.0291

0.0258

0.0258

0.0006

Triphenyl phosphate

     

0.0406

0.1250

0.1250

0.0154

0.0154

0.0063

  1. df dilution factor