Substance | Structure | CAS RN | Usage/origin | Mode of action | Toxic ratio |
---|---|---|---|---|---|
Benzo[a]pyrene | 50-32-8 | PAH, incomplete burning | Epoxide reacts with DNA and produces carcinogenic adduct | * | |
Benzo[b]fluoranthene | 205-99-2 | PAH, incomplete burning | Mutagenic | * | |
Bisphenol A | 80-05-7 | Polymer synthesis | Binding to estrogen-related receptors | 5.18E−01 | |
Carbendazim | 10605-21-7 | Fungicide | Inhibitor of mitosis and cell division | 1.51E+03 | |
Chlorophene | 120-32-1 | Antiseptic drug, disinfectant | Unknown | 1.94E+00 | |
Cyprodinil | 121552-61-2 | Fungicide | Inhibition of methionine biosynthesis | 9.34E+00 | |
Diazinon | 333-41-5 | Insecticide | Inhibition of acetylcholinesterase | 8.17E−01 | |
Diclofenac sodium salt | 15307-79-6 | Pharmaceutical | Inhibition of cyclooxygenase I and II, non-steroidal anti-inflammatory drug (NSAID) | 6.54E+02 | |
Diuron | 330-54-1 | Herbicide | Inhibition of photosynthesis: blocking of plastoquinone binding site of PSII | 5.40E+03 | |
Genistein | 446-72-0 | Antineoplastic agent | Inhibition of protein-tyrosine kinase and topoisomerase II: induction of G2-phase arrest in human and mice | 2.21E+02 | |
Naphthalene |
| 91-20-3 | Industry, insecticide | Epoxide induces hemolysis, induces narcosis | 1.20E+00 |
Naproxen sodium salt | 26159-34-2 | Pharmaceutical | Inhibition of cyclooxygenase I and II, non-steroidal anti-inflammatory drug (NSAID) | 1.09E+02 | |
Propiconazole | 60207-90-1 | Fungicide | Inhibition of ergosterol biosynthesis | 5.34E−01 | |
Triclosan | 3380-34-5 | Anti-infective agent, antiseptic drug, disinfectant | Binding of bacterial enoyl-acyl carrier protein reductase enzyme | 8.85E−01 | |
Triphenyl phosphate | 115-86-6 | Flame retardant, plasticizer | Neurotoxicity, developmental toxicity, metabolic disruption, endocrine activity, genotoxicity and estrogenic activity | 1.56E+00 |