Adverse effects in the fish embryo acute toxicity (FET) test: a catalogue of unspecific morphological changes versus more specific effects in zebrafish (Danio rerio) embryos

Environmental Sciences Europe

Table 2 Summary of morphological alterations in zebrafish (Danio rerio) embryos after 96 or 120/144 h exposure

The four core endpoints listed by OECD TG 236 (OECD, 2013) are indicated in bold. Frequency of occurrence: —frequent and/or at concentrations < LC₁₀; — ≤ 20% of exposed organisms and/or only at concentrations > LC₁₀; —not observed for this compound
* Additional determination at 120 and/or 144 hpf (cf. Table 1); ^# no symptoms of acute lethality at highest solubility in a final DMSO concentration of 1 %; ^$ no differentiation for specific spinal cord deformations; endpoints grouped under general “spinal cord malformation”