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Fig. 2 | Environmental Sciences Europe

Fig. 2

From: Diuron modulates the DNA methylation status of the ILT7 and TRAIL/TNFSF10 genes and decreases the killing activity of plasmacytoid dendritic cells

Fig. 2

Diuron promotes the decrease of 5mC in pDC via the TET2 overexpression. a Graph illustrates the Diuron-induced decease of 5-methylcytosine (5mC) in pDC exposed to Diuron. Ctrl represents control exposure performed with DMSO. ND: not detected. b Graph illustrates the fold change expression of mRNA encoding for the major DNA methylation players that are DNMT1, DNMT3A, DNMT3B, TET1, TET2 and TET3 compared to control. Ctrl represents control exposure performed with DMSO. c Graph from ELISA analysis illustrates the Diuron-induced increase of TET2 in pDC exposed to Diuron. Ctrl represents control exposure performed with DMSO

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