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Table 8 Toxicity of tylosin tartrate (mg/kg soil dry mass) toward six plant species assessed in standard plant tests

From: Results of extended plant tests using more realistic exposure scenarios for improving environmental risk assessment of veterinary pharmaceuticals

Species A. cepa A. sativa B. napus S. lycopersicum P. vulgaris T. pratense
Emergence
NOEC ≥250 ≥800 ≥144 ≥144 ≥800 ≥83.3
EC10 n.d. n.d. n.d. n.d. n.d. n.d.
(–) (–) (–) (–) (–) (–)
EC50 n.d. n.d. n.d. n.d. n.d. n.d.
(–) (–) (–) (–) (–) (–)
Post-emergence survival
NOEC 83.3 ≥800 83.3 ≥144 ≥800 48.1
EC10 71.2 n.d. n.d. 104 n.d. 28.1
(n.d.) (–) (–) (n.d.) (–) (n.d.)
EC50 135 n.d. 82.6 n.d. n.d. 57.6
(n.d.) (–) (n.d.) (–) (–) (n.d.)
Shoot length
NOEC 27.8 200 48.1 72.2 100 16.0
EC10 14.5a 565 54.9 63.2 32.8a 11.7
(0.1–32.3) (n.d.) (53.7–55.9) (45.7–74.8) (1.0–82.0) (5.5–17.2)
EC50 82.9 n.d. 96.0 127 434 49.8
(45.8–344) (–) (94.9–97.2) (115–147) (253–1341) (39.9–66.4)
Biomass
NOEC 27.8 50 48.1 ≥144 ≥800 16.0
EC10 10.9a 113 35.2 45.4 9.1a 7.7
(0.1–22.6) (14.5–203) (34.8–35.5) (40.5–49.5) (3.0–17.4) (0.1–15.3)
EC50 41.3 603 61.9 74.0 107 23.5
(15.8–63.3) (405–1394) (61.7–62.2) (70.5–77.6) (79.4–137) (3.6–103)
Valid: Yes Yes No (60 % emerged) No (60 % emerged) No (58 % emerged) Yes
Application range 27.8–250 50.0–800 16.0–144 36.1–144 50.0–800 9.30–83.3
  1. Effective concentrations (EC10, EC50 with 95 % confidence interval) and NOEC based on nominal test concentrations with 95 % confidence intervals (CI)
  2. n.d. not determined due to inappropriate data
  3. aExtrapolated value (beyond tested concentration range)