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Table 7 Toxicity of florfenicol (mg/kg soil dry mass) toward six plant species assessed in standard plant tests

From: Results of extended plant tests using more realistic exposure scenarios for improving environmental risk assessment of veterinary pharmaceuticals

Species A. cepa A. sativa B. napus S. alba S. lycopersicum P. vulgaris
Emergence
NOEC ≥5.00 ≥5.00 ≥5.00 0.56 <0.06 1.67
EC10 6.81 0.34 0.01 0.12 n.d. 0.57
(n.d.) (0.0–0.12) (n.d.) (0.03–0.25) (–) (0.13–1.13)
EC50 n.d. >5.00 >5.00 1.46 >5.00 >5.00
(–) (–) (–) (0.84–3.11) (–) (–)
Post-emergence survival
NOEC 1.67 ≥5.00 1.67 0.56 0.56 ≥5.00
EC10 0.35 2.28 0.71 0.24 0.43 n.d.
(0.06–0.75) (0.04–303) (n.d.) (0.09–0.36) (0.09–0.85) (–)
EC50 4.82 >5.00 2.71 0.6 3.43 n.d.
(2.13–35.8) (–) (n.d.) (0.40–1.00) (1.75–14.9) (–)
Shoot length
NOEC 0.19 ≥5.00 0.06 0.19 0.56 0.56
EC10 0.16 >5.00 0.06 0.14 0.25 0.74
(0.14–0.19) (–) (0.0–0.17) (n.d.) (n.d.) (0.42–1.03)
EC50 2.57 n.d. 0.93 0.60 1.83 2.86
(2.36–2.80) (–) (0.46–2.11) (n.d.) (n.d.) (2.35–3.53)
Biomass
NOEC 0.06 1.67 <0.06 0.19 0.56 0.56
EC10 0.06 0.58 0.05 0.07 0.46 0.76
(0.04–0.09) (n.d.) (0.01–0.09) (n.d.) (n.d.) (0.36–1.12)
EC50 0.75 >5.00 0.25 0.32 0.76 2.59
(0.63–0.89) (–) (0.16–0.38) (n.d.) (n.d.) (2.02–3.36)
Valid Yes Yes Yes Yes Yes Yes
  1. Effect concentrations (EC10, EC50 with 95 % confidence interval) and NOEC based on nominal test concentrations with 95 % confidence intervals (CI)
  2. Florfenicol application range (all species): 0.06–5.0 mg/kg
  3. n.d. not determined due to inappropriate data