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Table 3 Toxicological data for antiepileptic drugs, investigated in this study, regarding D. rerio embryo test

From: Screening for ecotoxicological effects of antiepileptic drugs in biologically treated waste water originating from an epilepsy ward by Danio rerio embryos

Test

Species

Endpoint (time)

Endpoint

Effect concentration (μg L-1)

Carbamazepine

Fish (early life stage)

D. rerio

LOEC (10 days)

Embryos and larvae mortality

50,000 [12]

EC50 (72 h)

Growth retardation

86,500 [35]

EC20 (72 h)

Tail malformation

17,500 [36]

EC50 (72 h)

Tail malformation

52,500 [36]

Phenytoin

Fish (early life stage)

D. rerio

EC20 (72 h)

Tail malformation

10,000 [36]

  

EC50 (72 h)

Tail malformation

97,400 [36]