Rank | Guideline study | Non-guideline | GLP with QA/QC | Spirit of GLP full protocol and raw data | Minor issues in the methods but otherwise clear | Major issues in the methods or reporting | Reliability of data (from [30]) |
---|---|---|---|---|---|---|---|
1 | X | Â | X | Â | Â | Â | Without restrictions |
 | X | X |  |  |  | ||
X | Â | Â | X | Â | Â | ||
 | X |  | X |  |  | ||
2 | Â | Â | Â | Â | X | Â | With restriction |
3 | Â | Â | Â | Â | Â | X | Not reliable |
4 | Â | Â | Â | Â | Â | Â | Not assignable |