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Figure 2 | Environmental Sciences Europe

Figure 2

From: REP-LECOTOX: an example of FP 6 INCO project to strengthen ecotoxicological research in WBC (Western Balkan countries)

Figure 2

Effect of atrazine on gene expression. Effect on gene expression of luteinizing hormone receptor (LHR), scavenger receptor-B1(SR-B1), steroidogenic acute regulatory protein (StAR), translocator protein (TSPO), steroidogenic factor-1 (SF-1), phosphodiesterase-4B (PDE4B), 3β-hydroxysteroiddehydrogenase (HSD), cytochrome P450 (CYP) 17A1, 17βHSD in Leydig cells of control and treated rats (50 and 200 mg/kg atrazine by gavage from postnatal day 23 to 50). The transcription of LHR gene in Leydig cells of atrazine-treated rats was downregulated in a dose-dependent manner, which could be the reason for reduction in cAMP level and expression of cAMP dependent genes R eproduced with permission from [33].)

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