Toxicology of perfluorinated compounds

Environmental Sciences Europe

Table 19 Elimination half-lives by various species according to perfluorinated compound and gender

Species	PFOS	PFOA		PFHxS		PFBA		PFBS	References
	M/F	F	M	F	M	F	M	M/F
Chicken Chick	125 days 16 days	-	4.6 days 3.9 days	-	-	-	-	-	Yoo et al. [109]; Yeung et al. [284]
Rat	100 days	2 to 4 h	4 to 6 days	-	-	1.6 to 1.8 h	7 to 9 h	4.5 h (M) 4 h (F)	Chang et al. [285]; Johnson et al. [98]; Olsen et al. [131]
Mouse	-	17 days	19 days	-	-	3 h	7 h	-	Chang et al. [285]; Lau et al. [161]
Rabbit	-	7 h	5.5 h	-	-	-	-	-	Hundley et al. [133]
Dog	-	8 to 13 days	20 to 30 days	-	-	-	-	-	Hanhijarvi et al. [286]
Monkey	150 days	30 days	21 days	87 days	141 days	1.7 days	-	3.5 to 4 days 4 days (M) 3.5 days (M)	Butenhoff et al. [125]; Chang et al. [285]; Buttenhoff et al. [283]; Olsen et al. [85]; Seacat et al. [128]; Olsen et al. [131]
Human	5.4 years	-	3.8 years	-	8.5 years	-	-	30 days 25.8 days	Olsen et al. [85, 131, 132]

F, female; M, male; PFBA, perfluorobutane acid; (from Lau et al. [115] amended and expanded).