Predicting the aquatic toxicity of commercial pesticide mixtures

Environmental Sciences Europe

Table 5 Aquatic toxicity of combination products with iodosulfuron and of the active substances contained therein

	*Lemna* growth inhibition	Algal growth inhibition	Acute toxicity to *Daphnia*	Acute toxicity to fish
Iodosulfuron (0.030) and Foramsulfuron (0.970)	EC₅₀: 0.001 MDR: 0.57	EC₅₀: n.a. MDR: n.a.	EC₅₀: 0.102 MDR: > 982	LC₅₀: 0.243 MDR: > 412
Iodosulfuron (0.031) and Foramsulfuron (0.969)	EC₅₀: 0.0008 MDR: 0.85	EC₅₀: 0.229 MDR: 7.77	EC₅₀: n.a. MDR: n.a.	LC₅₀: 0.805 MDR: > 124
Iodosulfuron (0.085) and Amidosulfuron (0.915)	EC₅₀: 0.0015 MDR: 4.43	EC₅₀: 0.359 MDR: 2.07	EC₅₀: 0.437 MDR: > 130	LC₅₀: 1.78 MDR: > 151
Iodosulfuron (0.039) and Amidosulfuron (0.299) and Propoxycarbazone (0.662)	EC₅₀: 0.0032 MDR: 1.87	EC₅₀: n.a. MDR: n.a.	EC₅₀: 7.94 MDR: > 10.4	LC₅₀: 5.67 MDR: > 18.1
Iodosulfuron (0.055) and Propoxycarbazone (0.945)	EC₅₀: 0.006 MDR: 0.84	EC₅₀: 1.63 MDR: 0.44	EC₅₀: 5.29 MDR: > 20.5	LC₅₀: 2.21 MDR: > 36.2
Iodosulfuron	0.00083	0.064 (0.07)^a	> 100	> 100
Foramsulfuron	0.00065	12.5	> 100	> 100
Amidosulfuron	0.0176	47.0	55.0	> 320
Propoxycarbazone	0.0064	1.57	> 107	> 77.2

Given are E(L)C₅₀ values (milligrams of the sum of a.s. per liter, mg ∑a.s./L) of herbicidal combination products that contain iodosulfuron and their model deviation ratio (MDR), based on the data set "most similar endpoints". In addition, the toxicity of all active substances (EC₅₀ in milligrams of a.s. per liter) contained in these products is provided. All a.s. in these products have the same herbicidal mode of action (inhibitor of branched chain amino acid synthesis).
n.a., no data available for the product. ^aValue from another test used for the last product