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Environmental Sciences Europe

Table 2 Frequency of underestimating product toxicity based on the data set "most similar endpoints"

From: Predicting the aquatic toxicity of commercial pesticide mixtures

 

Percentage (%) of MDR

 

> 2

> 5

> 10

> 100

Algal growth inhibition

    

Herbicidal products (58)

25.9

12.1

6.9

0.0

Fungicidal products (51)

37.2

15.7

9.8

2.0

Lemna growth inhibition

    

Herbicidal products (32)

9.4

0.0

0.0

0.0

Daphnia acute toxicity

    

Herbicidal products (59)

35.6

30.5

25.4

8.5

Fungicidal products (53)

13.2

0.0

0.0

0.0

Fish acute toxicity

    

Herbicidal products (61)

26.2

21.3

21.3

13.1

Fungicidal products (52)

19.2

9.6

1.9

0.0

Daphnia chronic toxicity

    

Herbicidal products (25)

44.0

24.0

16.0

12.0

Fungicidal products (16)

37.5

31.3

31.3

12.5

Fish chronic toxicity

    

Herbicidal products (20)

50.0

20.0

20.0

10.0

Fungicidal products (14)

50.0

28.6

21.4

0.0

  1. Given is the percentage of model deviation ratios (MDR), including censored and non-censored data, that were determined as being greater than the value of 2, 5, 10, or 100, respectively, for each of the six assessed endpoints using the data set compiling toxicity measures derived in tests with the individual active substances as similar as possible to those conducted with the products. Percentage MDR is related to the number of herbicidal and fungicidal combination products (indicated in parentheses) for which data for the product and all active substances were available for the given endpoint.
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