Predicting the aquatic toxicity of commercial pesticide mixtures

Environmental Sciences Europe

Table 1 Composition of herbicidal and fungicidal combination products

	Herbicides	Fungicides
Number of combination products (total)	69	58
- with similar MoA	26	6
- with dissimilar MoA	43	52
Number of different a.s.	60	60
Number of represented MoA groups	14	17
Similar MoA combinations (number of products)	O (10), B(11), C (4), F1 (1)	G1 (6)
Two most frequent dissimilar MoA combinations (number of products)	O and C (5), O and B (4)	G1 and C3 (9), G1 and G2 (6)
Number of products with unique MoA combination	17	17
Number of combination products here assessed	66	53

Given is the number of originally authorized combination products that contain a.s. with a similar or a dissimilar pesticidal mode of action (MoA), respectively. In addition, the number of different a.s. and MoA groups represented in the combination products is indicated together with the MoA combination most frequently represented and the number of products with a MoA combination encountered only once. Classification of pesticidal mode of action was done according to HRAC [16] and FRAC [17]: HRC group O, synthetic auxin; HRAC group B, inhibitor of branched chain amino acid synthesis (ALS inhibitor); HRAC group C, inhibitor of photosystem II; HRAC group F1, inhibitor of carotenoid synthesis; FRAC group G1, inhibitor of C14-demethylase in ergosterol biosynthesis (DMI fungicide); FRAC group C3, inhibitor of cytochrome c oxidoreductase at complex III in the mitochondrial electron transport; FRAC group G2, inhibitor of Δ¹⁴-reductase and Δ⁸ to Δ⁷-isomerase in ergosterol biosynthesis.