From: Pesticides, cancer, and oxidative stress: an application of machine learning to NHANES data
 |  |  | Colon cancer | Skin cancer (non-melanoma) | Melanoma | Skin cancer (other types) | Prostate cancer | Breast cancer | Cervix cancer | P value |
---|---|---|---|---|---|---|---|---|---|---|
2,4-D | ALT (U/L) | 1 |  | 3.469 (3.448–3.490) | 1.344 (1.340–1.348) | 1.083 (1.079–1.087) | 13.314 (13.314–13.496) | 0.400 (0.399–0.400) | 5.540 (5.495–5.586) | 0.001 |
 |  | 2 | 0.692 (0.689–0.696) | 0.596 (0.594–0.598) | 0.39 (0.389–0.391) | 3.442 (3.425–3.460) | 1.248 (1.242–1.253) | 1.296 (1.293–1.300) | 0.318 (0.317–0.319) |  |
 |  | 3 | 1.29 (1.285–1.294) | 0.504 (0.501–0.506) | 6.595 (6.568–6.622) | 0.348 (0.347–0.349) | 3.148 (3.127–3.169) | 0.342 (0.341–0.343) | 3.379 (3.357–3.400) |  |
 |  | 4 | 2.917 (2.886–2.949) | 1.169 (1.160–1.178) | 1.369 (1.365–1.372) | 4.737 (4.702–4.773) |  | 0.960 (0.959–0.960) |  |  |
 | AST (U/L) | 1 |  |  | 2.254 (2.244–2.264) | 5.142 (5.108–5.177) | 3.613 (3.583–3.643) | 0.614 (0.612–0.615) | 0.924 (0.921–0.927) |  |
 |  | 2 | 1.105 (1.101–1.109) | 1.545 (1.538–1.552) | 1.688 (1.684–1.693) | 1.017 (1.013–1.021) | 1.388 (1.382–1.395) | 0.360 (0.359–0.361) | 0.770 (0.767–0.773) |  |
 |  | 3 | 1.299 (1.292–1.306) | 0.125 (0.124–0.126) | 0.857 (0.855–0.858) | 0.574 (0.573–0.576) | 5.467 (5.427–5.507) | 0.865 (0.863–0.867) | 1.014 (1.009–1.019) |  |
 |  | 4 | 4.119 (4.087–4.151) | 1.836 (1.822–1.850) | 1.050 (1.048–1.053) | 3.301 (3.276–3.326) | 9.143 (9.047–9.241) | 1.775 (1.768–1.782) | 3.411 (3.384–3.438) |  |
 | GGT (U/L) | 1 | 0.269 (0.267–0.270) | 1.275 (1.269–1.281) | 1.525 (1.522–1.529) | 1.273 (1.268–1.277) |  | 0.668 (0.667–0.670) | 0.260 (0.259–0.261) |  |
 |  | 2 |  |  | 0.642 (0.641–0.643) |  | 1.143 (1.137–1.148) | 0.914 (0.911–0.916) |  |  |
 |  | 3 | 2.681 (2.666–2.697) | 0.59 (0.58–0.59) | 1.073 (1.070–1.076) | 0.742 (0.739–0.744) | 8.740 (8.654–8.827) | 0.568 (0.567–0.570) | 1.359 (1.350–1.367) |  |
 |  | 4 | 3.368 (3.346–3.389) | 0.136 (0.135–0.137) |  | 0.389 (0.388–0.391) | 2.365 (2.352–2.378) | 0.506 (0.505–0.507) | 7.023 (6.969–7.078) |  |
4-fluoro-3-phenoxybenzoic | AST (U/L) | 1 | 1.805 (1.788–1.823) |  | 1.762 (1.753–1.771) |  | 7.705 (7.667–7.743) | 0.225 (0.223–0.227) | 2.092 (2.082–2.101) | 0.001 |
 |  | 2 | 1.452 (1.445–1.459) | 3.533 (3.519–3.547) | 0.863 (0.859–0.866) | 0.667 (0.663–0.671) | 0.692 (0.687–0.697) | 0.473 (0.470–0.475) |  |  |
 |  | 3 |  |  | 2.183 (2.178–2.188) |  | 0.965 (0.960–0.970) | 1.460 (1.454–1.465) | 20.837 (20.744–20.932) |  |
 |  | 4 | 3.821 (3.804–3.838) |  | 0.441 (0.439–0.443) |  | 0.420 (0.416–0.424) | 1.770 (1.763–1.778) |  |  |
 | Iron, refigerated (μmol/L) | 1 | 3.132 (3.106–3.158) | 1.002 (1.002–1.002) | 1.627 (1.623–1.632) |  |  | 1.481 (1.476–1.485) | 3.017 (3.002–3.031) |  |
 |  | 2 | 2.328 (2.315–2.340) |  | 1.530 (1.526–1.534) |  | 0.465 (0.461–0.468) | 0.353 (0.350–0.356) |  |  |
 |  | 3 |  | 5.051 (5.027–5.075) | 0.471 (0.468–0.473) | 0.651 (0.647–0.655) | 2.538 (2.524–2.553) | 1.356 (1.351–1.362) | 21.223 (21.128–21.319) |  |
 |  | 4 | 1.956 (1.948–1.964) | 1.686 (1.676–1.697) | 1.230 (1.226–1.235) |  | 6.596 (6.567–6.625) |  |  |  |
3-phenoxybenzoic acid | ALT (U/L) | 1 | 0.682 (0.678–0.685) | 1.456 (1.447–1.465) | 0.279 (0.278–0.279) | 4.553 (4.517–4.590) | 0.367 (0.366–0.369) | 1.094 (1.091–1.097) |  | 0.001 |
 |  | 2 | 0.671 (0.667–0.675) | 0.315 (0.314–0.316) | 0.247 (0.246–0.247) | 1.563 (1.556–1.571) | 4.697 (4.655–4.740) | 0.552 (0.550–0.553) | 0.699 (0.697–0.701) |  |
 |  | 3 | 12.524 (12.379–12.672) | 0.583 (0.580–0.586) | 2.192 (2.185–2.199) | 0.641 (0.638–0.643) | 7.433 (7.355–7.513) | 0.944 (0.941–0.948) | 3.788 (3.755–3.822) |  |
 |  | 4 | 2.302 (2.274–2.330) |  | 0.841 (0.839–0.843) | 0.901 (0.897–0.905) | 1.310 (1.303–1.317) | 0.188 (0.187–0.188) |  |  |
 | GGT (U/L) | 1 | 0.932 (0.926–0.938) | 0.660 (0.657–0.663) | 0.466 (0.465–0.467) | 0.592 (0.590–0.594) |  | 0.541 (0.540–0.543) | 0.490 (0.489–0.492) |  |
 |  | 2 | 0.894 (0.888–0.900) | 2.125 (2.113–2.137) | 0.527 (0.526–0.528) |  | 0.565 (0.563–0.568) | 0.445 (0.444–0.447) |  |  |
 |  | 3 | 0.861 (0.856–0.865) | 0.027 (0.027–0.028) | 0.454 (0.452–0.455) | 1.040 (1.036–1.044) |  | 1.874 (1.865–1.883) |  |  |
 |  | 4 |  |  | 1.270 (1.265–1.274) | 1.495 (1.486–1.503) | 1.150 (1.145–1.156) | 0.608 (0.606–0.609) |  |  |
 | Iron, refigerated (μmol/L) | 1 |  | 0.049 (0.049–0.050) | 0.498 (0.496–0.499) |  | 0.800 (0.796–0.803) | 0.370 (0.369–0.371) |  |  |
 |  | 2 | 1.071 (1.065–1.077) | 0.276 (0.275–0.277) | 0.202 (0.202–0.203) | 2.249 (2.238–2.260) | 1.345 (1.338–1.353) | 1.018 (1.014–1.021) | 0.586 (0.584–0.588) |  |
 |  | 3 |  |  | 1.054 (1.050–1.057) | 0.938 (0.934–0.941) |  | 1.437 (1.432–1.443) |  |  |
 |  | 4 | 1.379 (1.374–1.385) |  |  | 0.508 (0.506–0.510) | 5.698 (5.637–5.759) | 0.510 (0.509–0.512) |  |  |
 | Uric acid (mg/dL) | 1 | 0.777 (0.772–0.783) | 0.329 (0.327–0.330) | 0.252 (0.252–0.253) | 1.952 (1.938–1.966) |  | 1.976 (1.968–1.984) | 5.525 (5.477–5.574) |  |
 |  | 2 |  | 0.490 (0.488–0.493) | 0.372 (0.371–0.373) | 1.742 (1.732–1.753) | 0.266 (0.264–0.267) | 1.210 (1.206–1.215) |  |  |
 |  | 3 | 0.558 (0.555–0.562) | 1.798 (1.787–1.808) | 2.187 (2.179–2.195) | 1.244 (1.239–1.249) | 7.846 (7.764–7.930) | 0.218 (0.217–0.219) | 0.035 (0.034–0.035) |  |
 |  | 4 | 1.703 (1.694–1.712) | 0.557 (0.554–0.561) | 0.884 (0.882–0.886) | 0.668 (0.666–0.671) | 1.629 (1.622–1.637) | 0.392 (0.391–0.393) |  |  |
Oxypyrimidine | AST (U/L) | 1 | 0.438 (0.432–0.443) |  | 0.085 (0.084–0.086) |  | 0.501 (0.497–0.505) | 0.718 (0.715–0.721) |  | 0.001 |
 |  | 2 | 1.722 (1.716–1.728) | 0.986 (0.982–0.990) | 0.406 (0.404–0.407) | 1.928(1.921–1.934) | 1.872 (1.865–1.880) | 1.123 (1.119–1.126) | 1.638 (1.631–1.645) |  |
 |  | 3 | 0.830 (0.825–0.834) | 0.095 (0.093–0.096) | 0.153 (0.153–0.154) | 1.378(1.374–1.382) | 1.737 (1.731–1.744) | 2.093 (2.088–2.099) | 5.878 (5.852–5.904) |  |
 |  | 4 | 0.358 (0.355–0.361) |  | 1.003 (1.000–1.005) | 0.399(0.396–0.402) | 4.416 (4.400–4.432) | 2.362 (2.355–2.370) | 4.974 (4.950–4.999) |  |
 | GGT (U/L) | 1 | 0.212 (0.209–0.215) | 1.486 (1.480–1.493) | 0.501 (0.500–0.503) |  | 0.256 (0.254–0.258) | 1.607 (1.603–1.612) | 0.947 (0.943–0.951) |  |
 |  | 2 |  | 0.076 (0.075–0.077) | 0.309 (0.307–0.310) | 4.180(4.165–4.194) | 2.726 (2.714–2.739) | 1.005 (1.001–1.009) |  |  |
 |  | 3 | 0.114 (0.112–0.115) |  | 0.479 (0.477–0.481) | 0.67(0.667–0.673) | 2.963 (2.952–2.974) | 2.089 (2.082–2.095) |  |  |
 |  | 4 | 3.349 (3.338–3.361) |  | 0.391 (0.390–0.393) | 2.160(2.152–2.169) | 3.053 (3.042–3.063) | 1.173 (1.170–1.176) | 5.845 (5.825–5.865) |  |
Paranitrophenol | Iron, refigerated (μmol/L) | 1 |  |  | 0.624 (0.622–0.626) |  | 3.072 (3.036–3.109) | 0.532 (0.530–0.534) |  | 0.001 |
 |  | 2 | 0.633 (0.629–0.638) | 0.331 (0.330–0.333) | 0.865 (0.862–0.868) |  |  |  | 1.002 (0.997–1.008) |  |
 |  | 3 | 0.581 (0.576–0.586) |  | 0.625 (0.623–0.627) | 1.020 (1.014–1.025) |  | 0.663 (0.661–0.666) | 0.75 (0.746–0.755) |  |
 |  | 4 | 0.560 (0.558–0.562) | 1.266 (1.257–1.275) | 0.996 (0.993–1.000) | 0.797 (0.792–0.801) | 2.347 (2.322–2.372) | 0.397 (0.369–0.399) |  |  |
Dichlorovnl-dimeth prop carboacid | Iron, refigerated (μmol/L) | 1 | 8.493 (8.428–8.559) |  | 3.886 (3.878–3.895) | 4.601 (4.567–4.626) | 0.359 (0.357–0.362) | 0.880(0.877–0.883) | 3.361 (3.346–3.376) | 0.001 |
 |  | 2 | 0.938 (0.933–0.944) | 0.342 (0.340–0.345) | 1.577 (1.573–1.580) | 0.889 (0.886–0.892) | 1.407 (1.401–1.413) | 0.665(0.662–0.667) | 1.912 (1.906–1.918) |  |
 |  | 3 |  | 3.832 (3.815–3.850) | 0.668 (0.665–0.670) | 0.253 (0.251–0.255) |  | 1.322(1.317–1.326) | 6.981 (6.952–7.011) |  |
 |  | 4 | 0.077 (0.076–0.077) |  | 2.347 (2.341–2.353) | 0.424 (0.421–0.427) | 0.321 (0.318–0.324) |  |  |  |
 | Uric acid (mg/dL) | 1 |  | 1.375 (1.368–1.382) | 0.910 (0.907–0.913) | 2.542 (2.530–2.555) | 0.650 (0.645–0.655) | 0.214 (0.213–0.216) | 3.631 (3.618–3.643) |  |
 |  | 2 |  |  | 1.276 (1.273–1.280) | 0.554 (0.551–0.557) |  | 0.966 (0.963–0.969) | 2.306 (2.299–2.313) |  |
 |  | 3 | 0.547 (0.542–0.552) | 1.066 (1.062–1.071) | 3.610 (3.602–3.618) | 0.832 (0.829–0.835) | 0.599 (0.596–0.602) | 1.019 (1.015–1.023) |  |  |
 |  | 4 | 1.185 (1.180–1.190) |  | 2.683 (2.677–2.688) | 0.135 (0.134–0.136) | 0.771 (0.768–0.775) | 0.281 (0.279–0.282) | 1.056 (1.048–1.064) |  |