Skip to main content
Environmental Sciences Europe
Fig. 2 | Environmental Sciences Europe

Fig. 2

From: Urinary metabolite of pesticide, 3,5,6-trichloropyridinol, is associated with all-cause but not with cancer mortality

Fig. 2

An illustration graph explaining the physiopathological mechanism between TCPY and mortality. TCPY decreased the levels of testosterone and estradiol, causing endocrine dysfunction. TCPY promoted the expression of IL-1α and Bax /Bcl-2, and caspase 9/3, which upregulated inflammatory responses and cell apoptosis. These results contributed to mortality collectively. IL-1α Interleukin-1α, Bcl2 B-cell lymphoma-2, Bax Bcl-2-associated X protein

Back to article page