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Table 1 Overview of ECx and NOEC/LOEC based on nominal fipronil concentrations determined for several endpoints in the long- and short-term exposure tests with C. dipterum

From: Chronic toxicity testing including transcriptomics-based molecular profiling in Cloeon dipterum

Test

Endpoint

Nominal fipronil concentrations

EC10

EC50

NOEC

LOEC

ng/L (95% cl)

ng/L

Long-term exposure

Larval development after 3 daysa

n. d

n. d

 ≥ 600

 > 600

Larval development after 7 daysb

23.0d) (4.00–47.0)

180 (117–292)

38.0

75.0

Larval development after 10 daysc

n. d

148 (80.0–270)

 < 38.0

 ≤ 38.0

Mortality after 38 days

n. d

185 (85.0–571)

38.0

75.0

Emergence after 38 days

n. d

160 (67.0–426)

38.0

75.0

Short-term exposure

Larval development after 3 daysa

n. d

n. d

 ≥ 300

 > 300

Larval development after 7 daysb

25.0d (n. d.)

n. d

75.0

150

Mortality after 7 days

n. d

n. d

 ≥ 300

 > 300

  1. cl = confidence limits; n. d. = not determined due to mathematical reasons
  2. aRespective larval stage L4
  3. bRespective larval stage L6
  4. cRespective larval stage L7
  5. dExtrapolated value