Multiple stressor effects of insecticide exposure and increased fine sediment deposition on the gene expression profiles of two freshwater invertebrate species

Environmental Sciences Europe

Table 1 Number of genes that showed antagonistic (A + /A−) or synergistic (S + /S−) stressor interactions

Interaction type	Low insecticide*sediment		Medium insecticide*sediment		High insecticide*sediment
Interaction type	L. basale	G. pulex	L. basale	G. pulex	L. basale	G. pulex
A-	12	53	13	37	80	22
A +	8	16	3	22	275	34
S-	–	6	-	5	–	2
S +	–	–	–	–	–	–
Total	20	75	16	64	355	58

Positive synergistic (S+) and positive antagonistic (A+) interactions were reported when the upregulation of a gene was stronger and weaker, respectively, than assumed based on additive stressor effects. Negative synergistic (S−) and negative antagonistic (A−) interactions were reported when the downregulation of a gene was stronger and weaker, respectively, than expected based on additivity