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Table 1 Fields of application of suspect and non-target screening in environmental monitoring

From: NORMAN guidance on suspect and non-target screening in environmental monitoring

Suspect screening

Non-target screening

Identifying expected contaminants in the environment for future monitoring

Identifying unknown or unexpected contaminants in the environment for future monitoring

Obtaining big picture of pollution by monitoring of large numbers of suspects, e.g., REACH chemicals, NORMAN SusDat

Identifying unknown chemicals from spills, specific emission sources and other events, such as stormwater run-off, industry outflow

Specific view on substance class related to specific chemistry, origins or usage, e.g., bisphenols, per- and polyfluorinated compounds, pesticides

Identifying causative chemicals for adverse effects observed through bioassays by effect-based tools including effect-directed analysis

Detecting exposure-relevant chemicals based on modelling approaches (emission, fate) in combination with chemical databases

Identifying causative chemicals for adverse effects observed in ecosystems by ecological monitoring

Detecting TPs or (disinfection) byproducts reported in literature or predicted by QSAR

Identifying new persistent and bioaccumulative compounds from multimedia and biota monitoring

Spatial monitoring along, e.g., river stretches

Spatial monitoring along, e.g., river stretches

Trend monitoring over time at one site

Trend monitoring over time at one site

Retrospective screening of emerging suspects in stored raw data to determine extent of previous contamination

Retrospective screening of unknown chemicals / masses of interest in stored raw data to determine extent of previous contamination

  1. Note that some applications apply to both types of screening