Endpoints | Hours post-fertilization (hpf) | |||||||
---|---|---|---|---|---|---|---|---|
8 h | 12 h | 24 h | 48 h | 60 h | 72 h | 84 h | 96 h | |
Mortality/coagulation* | X | X | X | X | X | X | X | X |
Hatching | X | X | X | X | ||||
Developmental retardations | ||||||||
Epiboly | X | |||||||
Gastrulation | X | |||||||
Formation of somites* | X | |||||||
Tail detachment* | X | |||||||
Spontaneous movements | X | |||||||
Eye development | X | |||||||
Heart beat rate (beats/min)* | X | |||||||
Otolith formation | X | |||||||
Occurrence of melanocytes | X | |||||||
Developmental failures | ||||||||
Edema (heart and yolk) | X | |||||||
Malformation of eyes | X | X | X | X | ||||
Spinal deformation (scoliosis) | X | X | X | X | ||||
Pigmentation failures | X | X | X | X |